The incidence and mortality of cancer are the major health issue worldwide. Apart from the
treatments developed to date, the unsatisfactory therapeutic effects of cancers have not …

Over the past decade, CRISPR-Cas systems have become indispensable tools for genetic
engineering and have been used in clinical trials for various diseases. Beyond genome …

Natural killer cells are potent cytotoxic lymphocytes specialized in recognizing and
eliminating transformed cells, and in orchestrating adaptive anti‐tumour immunity. However …

The recent developments in the study of clustered regularly interspaced short palindromic
repeats/associated protein 9 (CRISPR/Cas9) system have revolutionized the art of genome …

The expression of CDR1‑AS, a representative circular RNA, is closely linked with poor
prognosis in gastrointestinal cancers, such as colon, liver, and pancreatic cancers. Although …

The discovery of clustered regularly interspaced short palindromic repeats and CRISPR‐
associated protein 9 (CRISPR‐Cas9) technology has brought advances in the genetic …

Natural killer (NK) cells have recently gained popularity as an alternative for cancer
immunotherapy. Adoptive cell transfer employing NK cells offers a safer therapeutic option …

Simple Summary This review paper here describes the recent progress that has been made
in chimeric antigen receptor (CAR)-based therapies for treatment of tumors and the role of …

Background Gene knockout technologies involving programmable nucleases have been
used to create knockouts in several applications. Gene editing using Zinc-finger nucleases …

The recent advancements in cancer immunotherapy have spotlighted the potential of natural
killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK cells. These …