Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets

X Di, X Gao, L Peng, J Ai, X Jin, S Qi, H Li… - Signal transduction and …, 2023 - nature.com
Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

Tumor angiogenesis and anti-angiogenic strategies for cancer treatment

RI Teleanu, C Chircov, AM Grumezescu… - Journal of clinical …, 2019 - mdpi.com
Angiogenesis is the process through which novel blood vessels are formed from pre-existing
ones and it is involved in both physiological and pathological processes of the body …

Exosomes in angiogenesis and anti-angiogenic therapy in cancers

W Olejarz, G Kubiak-Tomaszewska… - International Journal of …, 2020 - mdpi.com
Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …

Bone marrow mesenchymal stem cell-derived small extracellular vesicles promote periodontal regeneration

L Liu, S Guo, W Shi, Q Liu, F Huo, Y Wu… - … Engineering Part A, 2021 - liebertpub.com
Bone marrow mesenchymal stem cell-derived small extracellular vesicles (BMSC-sEVs) can
be used as a potential cell-free strategy for periodontal tissue regeneration, and we aim to …

[HTML][HTML] Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine

A González-González, D García-Sánchez… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are the most frequently used stem cells in clinical trials due
to their easy isolation from various adult tissues, their ability of homing to injury sites and …

Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro

C Almeria, R Weiss, M Roy, C Tripisciano… - … in Bioengineering and …, 2019 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) display a variety of therapeutically relevant effects,
such as the induction of angiogenesis, particularly under hypoxic conditions. It is generally …

Mesenchymal stromal cell secretome for the treatment of immune-mediated inflammatory diseases: latest trends in isolation, content optimization and delivery …

E Munoz-Perez, A Gonzalez-Pujana, M Igartua… - Pharmaceutics, 2021 - mdpi.com
Considering the high prevalence and the complex pharmacological management of immune-
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …

[HTML][HTML] Future regenerative medicine developments and their therapeutic applications

AE Altyar, A El-Sayed, A Abdeen, M Piscopo… - Biomedicine & …, 2023 - Elsevier
Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …

Current trends and future perspective of mesenchymal stem cells and exosomes in corneal diseases

H Mansoor, HS Ong, AK Riau, TP Stanzel… - International journal of …, 2019 - mdpi.com
The corneal functions (transparency, refractivity and mechanical strength) deteriorate in
many corneal diseases but can be restored after corneal transplantation (penetrating and …

[HTML][HTML] PDLSCs regulate angiogenesis of periodontal ligaments via VEGF transferred by exosomes in periodontitis

Z Zhang, Y Shuai, F Zhou, J Yin, J Hu… - … journal of medical …, 2020 - ncbi.nlm.nih.gov
Abnormal angiogenesis is one of the significant features in periodontitis leading to
progressive inflammation, but angiogenic changes of periodontal ligaments under …