Asymmetric catalysis mediated by synthetic peptides, version 2.0: expansion of scope and mechanisms

AJ Metrano, AJ Chinn, CR Shugrue, EA Stone… - Chemical …, 2020 - ACS Publications
Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Enantioselective chemo‐and biocatalysis: partners in retrosynthesis

M Hönig, P Sondermann, NJ Turner… - Angewandte Chemie …, 2017 - Wiley Online Library
Recent developments of stereoselective biocatalytic and chemocatalytic methods are
discussed. The review provides a guide to the use of biocatalytic methods in the area of …

Catalytic asymmetric cyanation reactions

N Kurono, T Ohkuma - Acs Catalysis, 2016 - ACS Publications
Catalytic asymmetric cyanations of prochiral unsaturated compounds affording the
corresponding nitrile products in high enantiomeric excess (≥ 90% in general) are …

Asymmetric synthesis of tertiary alcohols and α-tertiary amines via Cu-catalyzed C− C bond formation to ketones and ketimines

M Shibasaki, M Kanai - Chemical reviews, 2008 - ACS Publications
Chiral tertiary alcohols and R-tertiary amines are important building blocks of naturally
occurring and artificial biologically active molecules. Although there are catalytic asymmetric …

Asymmetric organic catalysis with modified cinchona alkaloids

SK Tian, Y Chen, J Hang, L Tang… - Accounts of chemical …, 2004 - ACS Publications
Insights into the role played by modified cinchona alkaloids in the Sharpless asymmetric
dihydroxylation inspired studies of modified cinchona alkaloids as chiral organic catalysts …

Nucleophilic chiral amines as catalysts in asymmetric synthesis

S France, DJ Guerin, SJ Miller, T Lectka - Chemical reviews, 2003 - ACS Publications
Catalytic asymmetric synthesis is providing chemists with new and powerful tools for the
efficient synthesis of complex molecules. While many of the most notable catalytic systems …

Asymmetric catalysis for the construction of quaternary carbon centres: nucleophilic addition on ketones and ketimines

O Riant, J Hannedouche - Organic & biomolecular chemistry, 2007 - pubs.rsc.org
There is a growing need in organic synthesis for efficient methodologies for the asymmetric
synthesis of quaternary carbon centres. One of the most attractive and straightforward …

Lewis acid catalyzed asymmetric cyanohydrin synthesis

M North, DL Usanov, C Young - Chemical reviews, 2008 - ACS Publications
The addition of cyanide to a carbonyl compound to form a cyanohydrin is one of the
fundamental carbon-carbon bond forming reactions in organic chemistry1 and has …

Chemically catalyzed asymmetric cyanohydrin syntheses

JM Brunel, IP Holmes - Angewandte Chemie International …, 2004 - Wiley Online Library
Over the past two decades, significant advances have been made towards developing
chemically catalyzed asymmetric cyanohydrin syntheses. Preparations that were classically …

Towards perfect catalytic asymmetric synthesis: dual activation of the electrophile and the nucleophile

JA Ma, D Cahard - Angewandte Chemie International Edition, 2004 - Wiley Online Library
The design and development of new high‐performance catalysts for applications in
asymmetric catalytic reactions is of ongoing interest in organic chemistry. The combination of …