Secondary metabolites from hypocrealean entomopathogenic fungi: novel bioactive compounds

L Zhang, OE Fasoyin, I Molnár, Y Xu - Natural Product Reports, 2020 - pubs.rsc.org
Covering: 2014 up to the third quarter of 2019 Entomopathogens constitute a unique,
specialized trophic subgroup of fungi, most of whose members belong to the order …

Recent progress in the isolation, bioactivity, biosynthesis, and total synthesis of natural spiroketals

FM Zhang, SY Zhang, YQ Tu - Natural product reports, 2018 - pubs.rsc.org
Covering: 2011 to July 2017. Spiroketal (spiroacetal), a common moiety in numerous natural
products, drugs and functional molecules, has been a central topic in organic chemistry for a …

A polyketide cyclase that forms medium-ring lactones

DW Gao, CS Jamieson, G Wang, Y Yan… - Journal of the …, 2020 - ACS Publications
Medium-ring lactones are synthetically challenging due to unfavorable energetics involved
in cyclization. We have discovered a thioesterase enzyme DcsB, from the decarestrictine C1 …

Metabolites and Their Bioactivities from the Genus Cordyceps

SL Qu, SS Li, D Li, PJ Zhao - Microorganisms, 2022 - mdpi.com
The Cordyceps genus is a group of ascomycete parasitic fungi, and all known species of this
genus are endoparasites; they mainly feed on insects or arthropods and a few feed on other …

Applications of Claisen condensations in total synthesis of natural products. An old reaction, a new perspective

Z Khademi, MM Heravi - Tetrahedron, 2022 - Elsevier
The Claisen condensation involves the base-mediated reaction of an ester including α-
hydrogen atom with a similar molecule to generate α, β-keto ester. In this review, we focused …

Activities and metabolomics of Cordyceps gunnii under different culture conditions

SL Qu, J Xie, JT Wang, GH Li, XR Pan… - Frontiers in …, 2023 - frontiersin.org
Many active metabolites have been identified from various species of the fungal genus
Cordyceps. A predominant species of this genus is Cordyceps gunnii, but there are limited …

Chromosome level assembly and secondary metabolite potential of the parasitic fungus Cordyceps militaris

GJ Kramer, JR Nodwell - BMC genomics, 2017 - Springer
Background Cordyceps militaris is an insect pathogenic fungus that is prized for its use in
traditional medicine. This and other entomopathogenic fungi are understudied sources for …

Enzymatic ester bond formation strategies in fungal macrolide skeletons

JM Zhang, GY Yuan, Y Zou - Natural Product Reports, 2025 - pubs.rsc.org
Covering: up to August 2024Macrolides, the core skeletons of numerous marketed drugs
and bioactive natural products, have garnered considerable scientific interest owing to their …

Risks of mycotoxins from mycoinsecticides to humans

Q Hu, F Li, Y Zhang - BioMed Research International, 2016 - Wiley Online Library
There are more than thirty mycotoxins produced by fungal entomopathogens. Totally, they
belong to two classes, NRP and PK mycotoxins. Most of mycotoxins have not been paid …

Fungi: outstanding source of novel chemical scaffolds

Z Liu, JY Zhao, SF Sun, Y Li, YB Liu - Journal of Asian natural …, 2020 - Taylor & Francis
A large number of remarkable studies on the secondary metabolites of fungi have been
conducted in recent years. This review gives an overview of one hundred and sixty-seven …