Intranasal COVID-19 vaccine induces respiratory memory T cells and protects K18-hACE mice against SARS-CoV-2 infection

BK Diallo, C Ní Chasaide, TY Wong, P Schmitt, KS Lee… - npj Vaccines, 2023 - nature.com
Current COVID-19 vaccines prevent severe disease, but do not induce mucosal immunity or
prevent infection with SARS-CoV-2, especially with recent variants. Furthermore, serum …

A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies

P Kongsuphol, H Jia, HL Cheng, Y Gu… - Communications …, 2021 - nature.com
Abstract Background Neutralizing antibodies (NAbs) prevent pathogens from infecting host
cells. Detection of SARS-CoV-2 NAbs is critical to evaluate herd immunity and monitor …

Previous SARS-CoV-2 infection, age, and frailty are associated with 6-month vaccine-induced anti-spike antibody titer in nursing home residents

AH Dyer, C Noonan, M McElheron, I Batten… - Journal of the American …, 2022 - Elsevier
Objectives Older nursing home residents make up the population at greatest risk of morbidity
and mortality from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants

M Emmenegger, S Fiedler, SD Brugger, SRA Devenish… - Iscience, 2022 - cell.com
Summary The B. 1.1. 529 (omicron) variant has rapidly supplanted most other SARS-CoV-2
variants. Using microfluidics-based antibody affinity profiling (MAAP), we have characterized …

Immune response in vaccinated healthcare workers with frequent COVID-19 infections is characterised by blunted IFNγ and IL-2 responses to SARS-CoV-2 variants

L Townsend, J Dunne, J Sui, CS Perez, M McElheron… - Clinical …, 2024 - Elsevier
Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. Despite
widespread vaccination, some HCWs develop frequent symptomatic infection. We …

SARS-CoV-2 epidemiology, antibody dynamics, and neutralisation capacity in Irish healthcare workers in the era of booster COVID-19 vaccinations

J McGrath, C Kenny, CS Nielsen, L Domegan… - Frontiers in …, 2023 - frontiersin.org
Background The PRECISE Study, a multi-phase cross-sectional seroprevalence study of
anti-SARS-CoV-2 antibodies in Irish healthcare workers (HCW) investigated:(1) risk factors …

Clinical features related to severity and mortality among COVID-19 patients in a pre-vaccine period in Luanda, Angola

CS Sebastiao, A Cogle, ADA Teixeira… - Tropical Medicine and …, 2022 - mdpi.com
Background: Infection due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) is associated with clinical features of diverse severity. Few studies investigated the …

Severe acute respiratory syndrome coronavirus 2 antibody response after heterologous immunizations with ChAdOx1/BNT162b2 in end-stage renal disease patients …

DK Kim, SW Jung, JY Moon, KH Jeong… - Frontiers in …, 2022 - frontiersin.org
The Korean government decided to schedule heterologous vaccinations on dialysis patients
for early achievement of immunization against Coronavirus disease 2019 (COVID-19) …

Effect of Immunosuppression on the Immune Response to SARS-CoV-2 Infection and Vaccination

EJ Leacy, JW Teh, AM O'Rourke, G Brady… - International Journal of …, 2024 - mdpi.com
Immunosuppressive treatment in patients with rheumatic diseases can maintain disease
remission but also increase risk of infection. Their response to severe acute respiratory …

Point of care detection of SARS-CoV-2 antibodies and neutralisation capacity—lateral flow immunoassay evaluation compared to commercial assay to inform potential …

J McGrath, L O'Doherty, N Conlon, J Dunne… - Frontiers in Public …, 2023 - frontiersin.org
Introduction As the COVID-19 pandemic moves towards endemic status, testing strategies
are being de-escalated. A rapid and effective point of care test (POCT) assessment of SARS …