Depression is a highly prevalent disorder of the central nervous system. The
neuropsychiatric symptoms of clinical depression are persistent and include fatigue …

Depression stands as a prominent contributor to global disability, entailing an elevated risk
of suicide. Substantial evidence supports the notion that immune dysregulation may play a …

Persistent neuroinflammation following traumatic brain injury (TBI) remains to be a
significant challenge in the clinic, however, the role of meningeal lymphatics dysfunction …

The lymphatic vasculature plays a crucial role in fluid clearance and immune responses in
peripheral organs by connecting them to distal lymph nodes. Recently, attention has been …

Background Sepsis-associated encephalopathy (SAE) is an acute cerebral dysfunction
caused by sepsis. Neuroinflammation induced by sepsis is considered a potential …

Meningeal lymphatic vessels (mLVs) play a pivotal role in regulating metabolic waste from
cerebrospinal fluid (CSF). However, the current limitations in field of view and resolution of …

Objective Meningeal lymphatic vessels are predominantly located in the parasagittal dural
space (PSD); these vessels drain interstitial fluids out of the brain and contribute to the …

After aversive stress, people either choose to return to their previously familiar social
environment or tend to adopt temporary social withdrawal to buffer negative emotions …

This aim of this editorial is to highlight progress made in brain barrier and brain fluid
research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers …

The lymphatic system plays a vital role in the regulation of tissue fluid balance and the
immune response to inflammation or infection. The effects of lymphatic endothelial cells …