We now need more than ever to make genome analysis more intelligent. We need to read,
analyze, and interpret our genomes not only quickly, but also accurately and efficiently …

Abstract Approximately 5–10% of the human genome remains inaccessible due to the
presence of repetitive sequences such as segmental duplications and tandem repeat arrays …

Read mapping is a fundamental step in many genomics applications. It is used to identify
potential matches and differences between fragments (called reads) of a sequenced …

Long-read sequencing is now routinely used at scale for genomics and transcriptomics
applications. Mapping long reads or a draft genome assembly to a reference sequence is …

Long read sequencing technology is becoming increasingly popular for Precision Medicine
applications like Whole Genome Sequencing (WGS) and microbial abundance estimation …

Motivation Advances in genomics and sequencing technologies demand faster and more
scalable analysis methods that can process longer sequences with higher accuracy …

Read mapping is a fundamental, yet computationally-expensive step in many genomics
applications. It is used to identify potential matches and differences between fragments …

The MinION is a revolutionary handheld DNA sequencer that is inexpensive, portable, and
can perform real-time sequencing. MinION is increasingly used in Precision Medicine …

Generating the hash values of short subsequences, called seeds, enables quickly
identifying similarities between genomic sequences by matching seeds with a single lookup …

Nanopore sequencing is a widely-used high-throughput genome sequencing technology
that can sequence long fragments of a genome into raw electrical signals at low cost …