Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

Atrophy occurs in specific muscles with inactivity (for example, during plaster cast
immobilization) or denervation (for example, in patients with spinal cord injuries). Muscle …

Life expectancy is increasing worldwide, with a resultant increase in the elderly population.
Aging is characterized by the progressive loss of skeletal muscle mass and strength–a …

Efforts to develop a consensus definition are ongoing and will greatly facilitate the
development and testing of novel interventions for sarcopenia. Although pharmaceutical …

Abstract Changes in the neuromuscular system affecting the ageing motor unit manifest
structurally as a reduction in motor unit number secondary to motor neuron loss; fibre type …

Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …

The cellular basis of age-related tissue deterioration remains largely obscure. The ability to
activate compensatory mechanisms in response to environmental stress is an important …

Aging is associated with a progressive loss of muscle mass and strength and a decline in
neurophysiological functions. Age-related neuromuscular junction (NMJ) plays a key role in …

Age-related sarcopenia constitutes an important health problem associated with adverse
outcomes. Sarcopenia is closely associated with fat infiltration in muscle, which is …

Sarcopenia is the age-related loss of skeletal muscle mass and function. It is now
recognised as a major clinical problem for older people and research in the area is …