Hydrogels: properties and applications in biomedicine

TC Ho, CC Chang, HP Chan, TW Chung, CW Shu… - Molecules, 2022 - mdpi.com
Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures,
which can absorb relatively large amounts of fluid. Because of the high water content, soft …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Advances in drug delivery systems, challenges and future directions

TC Ezike, US Okpala, UL Onoja, CP Nwike, EC Ezeako… - Heliyon, 2023 - cell.com
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …

[HTML][HTML] In situ gelling drug delivery systems for topical drug delivery

OM Kolawole, MT Cook - European Journal of Pharmaceutics and …, 2023 - Elsevier
In situ gelling formulations are drug delivery systems which typically exist in a liquid form at
room temperature and change into gel state after application to the body in response to …

Advanced formulation approaches for ocular drug delivery: state-of-the-art and recent patents

EB Souto, J Dias-Ferreira, A López-Machado… - Pharmaceutics, 2019 - mdpi.com
The eye presents extensive perspectives and challenges for drug delivery, mainly because
of the extraordinary capacity, intrinsic to this path, for drugs to permeate into the main …

Hydrogel-based platforms for site-specific doxorubicin release in cancer therapy

C Zang, Y Tian, Y Tang, M Tang, D Yang… - Journal of Translational …, 2024 - Springer
Hydrogels are promising candidates for the delivery of therapeutics in the treatment of
human cancers. Regarding to the biocomaptiiblity, high drug and encapsulation efficacy and …

S-protected gellan gum: Decisive approach towards mucoadhesive antimicrobial vaginal films

A Jalil, MH Asim, NMN Le, F Laffleur… - International journal of …, 2019 - Elsevier
The aim of this study was to synthesize novel polymeric excipients forming mucoadhesive
films for treatment of vaginal microbial infections. 2-(2-Amino ethyldisulfanyl) nicotinic acid …

Recent advances in ocular drug delivery systems and targeting VEGF receptors for management of ocular angiogenesis: A comprehensive review

S Narayana, MG Ahmed, BHJ Gowda… - Future Journal of …, 2021 - Springer
Background Angiogenic ocular diseases address the main source of vision impairment or
irreversible vision loss. The angiogenesis process depends on the balance between the pro …

Comparative study of in situ gel formulation based on the physico-chemical aspect: Systematic review

IS Kurniawansyah, T Rusdiana, I Sopyan, IF Desy Arya… - Gels, 2023 - mdpi.com
In recent years, in situ gel delivery systems have received a great deal of attention among
pharmacists. The in situ gelation mechanism has several advantages over ointments, the …

Designing of a pH-Triggered Carbopol®/HPMC In Situ Gel for Ocular Delivery of Dorzolamide HCl: In Vitro, In Vivo, and Ex Vivo Evaluation

M Kouchak, M Mahmoodzadeh, F Farrahi - AAPS PharmSciTech, 2019 - Springer
Dorzolamide HCl (DRZ) ophthalmic drop is one of the most common glaucoma medications
which rapidly eliminates after instillation leading to short residence time of the drug on …