Learning from the exceptions: HIV remission in post-treatment controllers
B Etemad, E Esmaeilzadeh, JZ Li - Frontiers in immunology, 2019 - frontiersin.org
Among the top priorities of the HIV field is the search for therapeutic interventions that can
lead to sustained antiretroviral therapy (ART)-free HIV remission. Although the majority of …
lead to sustained antiretroviral therapy (ART)-free HIV remission. Although the majority of …
Paediatric HIV infection: the potential for cure
PJ Goulder, SR Lewin, EM Leitman - Nature Reviews Immunology, 2016 - nature.com
Recent anecdotal reports of HIV-infected children who received early antiretroviral therapy
(ART) and showed sustained control of viral replication even after ART discontinuation have …
(ART) and showed sustained control of viral replication even after ART discontinuation have …
Broadly neutralizing antibody treatment maintained HIV suppression in children with favorable reservoir characteristics in Botswana
RL Shapiro, G Ajibola, K Maswabi, M Hughes… - Science translational …, 2023 - science.org
Broadly neutralizing antibodies (bNAbs) may provide an alternative to standard antiretroviral
treatment (ART) for controlling HIV-1 replication and may have immunotherapeutic effects …
treatment (ART) for controlling HIV-1 replication and may have immunotherapeutic effects …
The epidemiology of adolescents living with perinatally acquired HIV: a cross-region global cohort analysis
… Initiative for Paediatric HIV Education and … - PLoS …, 2018 - journals.plos.org
Background Globally, the population of adolescents living with perinatally acquired HIV
(APHs) continues to expand. In this study, we pooled data from observational pediatric HIV …
(APHs) continues to expand. In this study, we pooled data from observational pediatric HIV …
Paediatric E uropean N etwork for T reatment of AIDS (PENTA) guidelines for treatment of paediatric HIV‐1 infection 2015: optimizing health in preparation for adult life
A Bamford, A Turkova, H Lyall, C Foster, N Klein… - HIV …, 2018 - Wiley Online Library
The 2015 Paediatric E uropean Network for Treatment of AIDS (PENTA) guidelines provide
practical recommendations on the management of HIV‐1 infection in children in E urope and …
practical recommendations on the management of HIV‐1 infection in children in E urope and …
A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation
Understanding HIV remission in rare individuals who initiated antiretroviral therapy (ART)
soon after infection and then discontinued, may inform HIV cure interventions. Here we …
soon after infection and then discontinued, may inform HIV cure interventions. Here we …
No evidence of HIV replication in children on antiretroviral therapy
GU Van Zyl, MG Katusiime, A Wiegand… - The Journal of …, 2017 - Am Soc Clin Investig
It remains controversial whether current antiretroviral therapy (ART) fully suppresses the
cycles of HIV replication and viral evolution in vivo. If replication persists in sanctuary sites …
cycles of HIV replication and viral evolution in vivo. If replication persists in sanctuary sites …
Influence of age at virologic control on peripheral blood human immunodeficiency virus reservoir size and serostatus in perinatally infected adolescents
Importance Combination antiretroviral therapy initiated within several weeks of human
immunodeficiency virus (HIV) infection in adults limits proviral reservoirs that preclude HIV …
immunodeficiency virus (HIV) infection in adults limits proviral reservoirs that preclude HIV …
Index case finding facilitates identification and linkage to care of children and young persons living with HIV/AIDS in Malawi
S Ahmed, RA Sabelli, K Simon… - Tropical Medicine & …, 2017 - Wiley Online Library
Objectives Evaluation of a novel index case finding and linkage‐to‐care programme to
identify and link HIV‐infected children (1–15 years) and young persons (> 15–24 years) to …
identify and link HIV‐infected children (1–15 years) and young persons (> 15–24 years) to …
Clinical trials of antiretroviral treatment interruption in HIV-infected individuals
Despite the benefits of antiretroviral therapy (ART) for people living with HIV, there has been
a long-standing research interest in interrupting ART as a strategy to minimize adverse …
a long-standing research interest in interrupting ART as a strategy to minimize adverse …