Cyclodextrins: Emerging medicines of the new millennium
SS Braga - Biomolecules, 2019 - mdpi.com
Cyclodextrins, since their discovery in the late 19th century, were mainly regarded as
excipients. Nevertheless, developments in cyclodextrin research have shown that some of …
excipients. Nevertheless, developments in cyclodextrin research have shown that some of …
A review on possible modes of action of chloroquine/hydroxychloroquine: repurposing against SAR-CoV-2 (COVID-19) pandemic
S Tripathy, B Dassarma, S Roy, H Chabalala… - International journal of …, 2020 - Elsevier
Chloroquine (CQ) and its analogue hydroxychloroquine (HCQ) have long been used
worldwide as frontline drugs for the treatment and prophylaxis of human malaria. Since the …
worldwide as frontline drugs for the treatment and prophylaxis of human malaria. Since the …
Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection
The recent emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) is
responsible for a worldwide pandemic. Given the global health emergency, drug …
responsible for a worldwide pandemic. Given the global health emergency, drug …
Structural dynamics of SARS-CoV-2 variants: A health monitoring strategy for anticipating Covid-19 outbreaks
Objectives the Covid-19 pandemic has been marked by sudden outbreaks of SARS-CoV-2
variants harboring mutations in both the N-terminal (NTD) and receptor binding (RBD) …
variants harboring mutations in both the N-terminal (NTD) and receptor binding (RBD) …
Membrane rafts: portals for viral entry
I Ripa, S Andreu, JA López-Guerrero… - Frontiers in …, 2021 - frontiersin.org
Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …
Synergistic antiviral effect of hydroxychloroquine and azithromycin in combination against SARS-CoV-2: What molecular dynamics studies of virus-host interactions …
The emergence of SARS-coronavirus-2 (SARS-CoV-2) has led to a global pandemic
disease referred to as coronavirus disease 19 (COVID-19). Hydroxychloroquine (CLQ …
disease referred to as coronavirus disease 19 (COVID-19). Hydroxychloroquine (CLQ …
[HTML][HTML] Dependence of SARS-CoV-2 infection on cholesterol-rich lipid raft and endosomal acidification
X Li, W Zhu, M Fan, J Zhang, Y Peng, F Huang… - Computational and …, 2021 - Elsevier
Coronavirus disease 2019 is a kind of viral pneumonia caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). However, the mechanism whereby SARS-CoV-2 …
syndrome coronavirus 2 (SARS-CoV-2). However, the mechanism whereby SARS-CoV-2 …
Initial step of virus entry: virion binding to cell-surface glycans
Virus infection is an intricate process that requires the concerted action of both viral and host
cell components. Entry of viruses into cells is initiated by interactions between viral proteins …
cell components. Entry of viruses into cells is initiated by interactions between viral proteins …
Role of lipid rafts in pathogen-host interaction-a mini review
R Kulkarni, EAC Wiemer, W Chang - Frontiers in Immunology, 2022 - frontiersin.org
Lipid rafts, also known as microdomains, are important components of cell membranes and
are enriched in cholesterol, glycophospholipids and receptors. They are involved in various …
are enriched in cholesterol, glycophospholipids and receptors. They are involved in various …
The Lord of the NanoRings: Cyclodextrins and the battle against SARS-CoV-2
A handful of singular structures and laws can be observed in nature. They are not always
evident but, once discovered, it seems obvious how to take advantage of them. In chemistry …
evident but, once discovered, it seems obvious how to take advantage of them. In chemistry …