Alzheimer's disease (AD) is a neurodegenerative disease with unknown pathogenesis and
complex pathological manifestations. At present, a large number of studies on targeted …

Cortactin fulfills many functions in various cell types. These functions have been considered
to derive from its ability to activate the Actin-related protein 2/3 (Arp2/3) complex, and are …

Actin remodeling plays an essential role in diverse cellular processes such as cell motility,
vesicle trafficking or cytokinesis. The scaffold protein and actin nucleation promoting factor …

p27Kip1 (p27) is a cyclin-CDK inhibitor and negative regulator of cell proliferation. p27 also
controls other cellular processes including migration and cytoplasmic p27 can act as an …

Cancer-derived small extracellular vesicles have been proposed as promising potential
biomarkers for diagnosis and prognosis of breast cancer (BC). We performed a proteomic …

Simple Summary Individualized medicine means understanding how each tumor is different
from normal cells and how each tumor is different from other tumors, including profiling …

Background Prostate cancer is one of the leading causes of cancer death in males. Recent
studies have reported aberrant expression of lncRNAs in prostate cancer. This study …

Chromosome translocations involving the MLL gene are common rearrangements in
leukemia. Such translocations fuse the MLL 5'-region to partner genes in frame, producing …

Anaplastic thyroid cancer (ATC) is an aggressive cancer with poor clinical prognosis.
However, mechanisms driving ATC aggressiveness is not well known. Components of the …

Neurite outgrowth is a crucial process in developing neurons for neural network formation.
Understanding the regulatory mechanisms of neurite outgrowth is essential for developing …