Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-
threatening. The continued emergence of antibiotic resistance, together with our increasing …

Bacteria and archaea rely on appendages called type IV pili (T4P) to participate in diverse
behaviors including surface sensing, biofilm formation, virulence, protein secretion and …

Clonal bacterial populations rely on transcriptional variation across individual cells to
produce specialized states that increase fitness. Understanding all cell states requires …

Advances in synthetic biology permit the genetic encoding of synthetic chemistries at
monomeric precision, enabling the synthesis of programmable proteins with tunable …

Urinary tract infections (UTIs) cause a substantial health care burden. UTIs (i) are most often
caused by uropathogenic Escherichia coli (UPEC),(ii) primarily affect otherwise healthy …

While biofilms formed by bacteria have received great attention due to their importance in
pathogenesis, much less research has been focused on the biofilms formed by archaea. It …

The recent revolution in cryo-electron microscopy (cryo-EM) has made it possible to
determine macromolecular structures directly from cell extracts. However, identifying the …

Acinetobacter baumannii is a gram-negative bacterium and a crucial opportunistic pathogen
in hospitals. A. baumannii infection has become a challenging problem in clinical practice …

The gut microbiome influences cancer development and the efficacy and safety of
chemotherapy but little is known about its effects on lymphoma. We obtained stool samples …

Multidrug-resistant Acinetobacter baumannii infections are an urgent clinical problem and
can cause difficult-to-treat nosocomial infections. During such infections, like catheter …