In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Cancer accounts for numerous deaths each year, and it is one of the most common causes
of death worldwide, despite many breakthroughs in the discovery of novel anticancer …

Thiazole is one of the most important scaffolds in heterocyclic chemistry and drug design
and discovery. It is widely found in diverse pharmacologically active substances and in …

Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …

This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …

Microtubules are protein biopolymers formed through polymerization of heterodimers of α-
and β-tubulins. Disruption of microtubules can induce cell cycle arrest in G 2-M phase and …

Currently, the development of anticancer drug resistance is significantly restricted the clinical
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …

Cancer has been the second heath killer being next only to cardiovascular diseases in
human society. Although many efforts have been taken for cancer therapy and many …

Microtubules are dynamic polymers that occur in eukaryotic cells and play important roles in
cell division, motility, transport and signaling. They form during the process of polymerization …

Background Abolition of cancer warrants effective treatment modalities directed towards
specific pathways dysregulated in tumor proliferation and survival. The antiapoptotic Bcl-2 …