T Bieber, E Feist, AD Irvine, M Harigai, E Haladyj… - Advances in …, 2022 - Springer
Baricitinib is an oral, selective inhibitor of Janus kinase (JAK) 1/JAK2 that transiently and reversibly inhibits many proinflammatory cytokines. This mechanism is a key mediator in a …
DMR Davis, AM Drucker, A Alikhan, L Bercovitch… - Journal of the American …, 2022 - Elsevier
Background Studies found associations between atopic dermatitis (AD) and various comorbidities. Objective To appraise evidence of the association between AD and …
EL Simpson, JR Parnes, D She, S Crouch… - Journal of the American …, 2019 - Elsevier
Background Tezepelumab (AMG 157/MEDI9929), a first-in-class monoclonal antibody, targets thymic stromal lymphopoietin, a cytokine that is implicated in the pathogenesis of …
Importance Janus kinase (JAK) inhibitors are an effective treatment option for patients with certain skin-related conditions, such as atopic dermatitis, alopecia areata, and vitiligo, but …
T Bieber, JP Thyssen, K Reich… - Journal of the …, 2021 - Wiley Online Library
Background Janus kinase (JAK) inhibition is a new mode of action in atopic dermatitis (AD); clarity about drug class safety considerations in the context of AD is important. Baricitinib, an …
AB Pavel, L Zhou, A Diaz, B Ungar, J Dan, H He… - Journal of the American …, 2020 - Elsevier
Background Moderate-to-severe atopic dermatitis (AD) is increasingly recognized as a systemic disease, largely due to proteomic blood studies. There are growing efforts to …
M Moyle, F Cevikbas, JL Harden… - Experimental …, 2019 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, systemic, inflammatory disease that affects the skin and is characterized by persistent itch and marked redness. AD is associated with an increased …
Background Atopic eczema is a common and debilitating condition associated with depression and anxiety, but the nature of this association remains unclear. Objective To …
T Bieber, AS Paller, K Kabashima… - Journal of the …, 2022 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, heterogenous, inflammatory skin disorder associated with a high skin‐related health burden, typically starting in childhood and often persisting …