Molecular and cellular insights into the development of uterine fibroids
Uterine leiomyomas represent the most common benign gynecologic tumor. These hormone-
dependent smooth-muscle formations occur with an estimated prevalence of~ 70% among …
dependent smooth-muscle formations occur with an estimated prevalence of~ 70% among …
The epidemiology and genetics of uterine leiomyoma
AK Styer, BR Rueda - Best practice & research Clinical obstetrics & …, 2016 - Elsevier
Highlights•Race/ethnicity is the most consistent factor associated with fibroid
development.•Direct cause of genetics and the genesis of fibroids remain uncertain.•Models …
development.•Direct cause of genetics and the genesis of fibroids remain uncertain.•Models …
Autophagy and oxidative stress in non-communicable diseases: a matter of the inflammatory state?
Abstract Non-communicable diseases (NCDs), also known as chronic diseases, are long-
lasting conditions that affect millions of people around the world. Different factors contribute …
lasting conditions that affect millions of people around the world. Different factors contribute …
Current challenges and future implications of exploiting the omics data into nutrigenetics and nutrigenomics for personalized diagnosis and nutrition-based care
V Singh - Nutrition, 2023 - Elsevier
Nutrigenetics and nutrigenomics, combined with the omics technologies, are a demanding
and an increasingly important field in personalizing nutrition-based care to understand an …
and an increasingly important field in personalizing nutrition-based care to understand an …
[HTML][HTML] Cell-free circulating tumor DNA analysis for breast cancer and its clinical utilization as a biomarker
R Wang, X Li, H Zhang, K Wang, J He - Oncotarget, 2017 - ncbi.nlm.nih.gov
Circulating tumor DNA (ctDNA) in the blood of cancer patients contains much information on
genetic and epigenetic profiles associated with cancer development, progression, and …
genetic and epigenetic profiles associated with cancer development, progression, and …
BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway
High-grade gliomas (HGG) afflict both children and adults and respond poorly to current
therapies. Epigenetic regulators have a role in gliomagenesis, but a broad, functional …
therapies. Epigenetic regulators have a role in gliomagenesis, but a broad, functional …
CRISPR/Cas9-mediated genome editing of epigenetic factors for cancer therapy
Advances in engineered recombinant nuclease have provided facile and reliable methods
for genome editing. Especially with the development of the CRISPR (clustered regularly …
for genome editing. Especially with the development of the CRISPR (clustered regularly …
Alcohol-induced epigenetic changes in cancer
RG Dumitrescu - Cancer Epigenetics for Precision Medicine: Methods …, 2018 - Springer
Chronic, heavy alcohol consumption is associated with serious negative health effects,
including the development of several cancer types. One of the pathways affected by alcohol …
including the development of several cancer types. One of the pathways affected by alcohol …
Promoter methylation of DNA damage repair (DDR) genes in human tumor entities: RBBP8/CtIP is almost exclusively methylated in bladder cancer
J Mijnes, J Veeck, NT Gaisa, E Burghardt… - Clinical …, 2018 - Springer
Background Genome-wide studies identified pan-cancer genes and shared biological
networks affected by epigenetic dysregulation among diverse tumor entities. Here, we …
networks affected by epigenetic dysregulation among diverse tumor entities. Here, we …
Prospects for incorporation of epigenetic biomarkers in human health and environmental risk assessment of chemicals
Epigenetic mechanisms have gained relevance in human health and environmental studies,
due to their pivotal role in disease, gene× environment interactions and adaptation to …
due to their pivotal role in disease, gene× environment interactions and adaptation to …