Self-Assembly of Amyloid-Beta (Aβ) Peptides from Solution to Near In Vivo Conditions

PH Nguyen, F Sterpone… - The Journal of Physical …, 2022 - ACS Publications
Understanding the atomistic resolution changes during the self-assembly of amyloid
peptides or proteins is important to develop compounds or conditions to alter the …

Liquid–liquid phase separation (llps)-driven fibrilization of amyloid-β protein

S Sudhakar, A Manohar, E Mani - ACS Chemical Neuroscience, 2023 - ACS Publications
Amyloid-β [Aβ (1–40)] aggregation into a fibrillar network is one of the major hallmarks of
Alzheimer's disease (AD). Recently, a few studies reported that polyphosphate (polyP), an …

Electroosmotic mixing of viscoplastic fluids in a microchannel

SK Mehta, PK Mondal - Physical Review Fluids, 2024 - APS
Viscoplastic fluids flow through a microfluidic channel having a built-in two-part cylinder
inside, while the upstream and downstream parts of the cylinder bear the surface potential of …

Computational assessment of the impact of Cu(II) and Al(III) on β-amyloid42 fibrils: Binding sites, structural stability, and possible physiological implications

L Roldán-Martín, M Sodupe, JD Maréchal - Frontiers in Neuroscience, 2023 - frontiersin.org
One of Alzheimer's disease major hallmarks is the aggregation of β-amyloid peptide, a
process in which metal ions play an important role. In the present work, an integrative …

Modeling Inhibitory Effects of Chlorogenic Acid on Amyloid Beta Aggregation

A Majid, S Garg - Industrial & Engineering Chemistry Research, 2024 - ACS Publications
Amyloid β (Aβ) aggregation is considered one of the major factors in Alzheimer's disease
(AD) pathogenesis. Seeking therapeutic molecules that could inhibit the aggregation …

Characterization of amyloid-like metal-amino acid assemblies with remarkable catalytic activity

OS Tiwari, E Gazit - Peptide Catalysts, Including Catalytic …, 2024 - books.google.com
Characterization of amyloid-like metal-amino acid assemblies with remarkable catalytic activity
Page 204 CHAPTER EIGHT Characterization of amyloid-like metal-amino acid assemblies …

Computational modelling of supramolecular metallopeptide assemblies

LR Martín, LR Santiago, IV Korendovych… - Methods in …, 2024 - Elsevier
Among the important questions in supramolecular peptide self-assemblies are their
interactions with metallic compounds and ions. In the last decade, intensive efforts have …

[HTML][HTML] Extracellular interplay of amyloid fibrils and neural cells

VP Zhdanov - Biosystems, 2023 - Elsevier
Some neurological disorders such eg as Alzheimer disease are accompanied by the
appearance of amyloid fibrils inside and outside cells. Herein, I present a generic coarse …