The immune microenvironment in gastric adenocarcinoma

Y Zavros, JL Merchant - Nature Reviews Gastroenterology & …, 2022 - nature.com
Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma
(GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal …

[HTML][HTML] Helicobacter pylori in human health and disease: Mechanisms for local gastric and systemic effects

D Bravo, A Hoare, C Soto, MA Valenzuela… - World journal of …, 2018 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is present in roughly 50% of the human population worldwide
and infection levels reach over 70% in developing countries. The infection has classically …

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Helicobacter pylori and gastrointestinal tract adenocarcinomas

RM Peek Jr, MJ Blaser - Nature Reviews Cancer, 2002 - nature.com
Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

Eradication of Helicobacter pylori and Gastric Cancer: A Controversial Relationship

M Piscione, M Mazzone, MC Di Marcantonio… - Frontiers in …, 2021 - frontiersin.org
Worldwide, gastric cancer (GC) represents the fifth cancer for incidence, and the third as
cause of death in developed countries. Indeed, it resulted in more than 780,000 deaths in …

[HTML][HTML] Helicobacter pylori persistence: biology and disease

MJ Blaser, JC Atherton - The Journal of clinical investigation, 2004 - Am Soc Clin Investig
Helicobacter pylori are bacteria that have coevolved with humans to be transmitted from
person to person and to persistently colonize the stomach. Their population structure is a …

Carcinogenesis of Helicobacter pylori

P Correa, JM Houghton - Gastroenterology, 2007 - Elsevier
Helicobacter infection is the leading cause of gastric cancer worldwide. Infection with this
ubiquitous bacterium incites a chronic active immune response that persists for the life of the …

Host-bacterial interactions in Helicobacter pylori infection

MR Amieva, EM El–Omar - Gastroenterology, 2008 - Elsevier
Helicobacter pylori are spiral-shaped gram-negative bacteria with polar flagella that live
near the surface of the human gastric mucosa. They have evolved intricate mechanisms to …

THE PATHOGENESIS OF HELICOBACTER PYLORI–INDUCED GASTRO-DUODENAL DISEASES

JC Atherton - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Helicobacter pylori is the main cause of peptic ulceration, distal gastric adenocarcinoma,
and gastric lymphoma. Only 15% of those colonized develop disease, and pathogenesis …

Helicobacter infection and gastric neoplasia

RM Peek Jr, JE Crabtree - The Journal of Pathology: A Journal …, 2006 - Wiley Online Library
Chronic gastritis induced by Helicobacter pylori is the strongest known risk factor for
adenocarcinoma of the distal stomach, yet only a minority of people who harbour this …