The essential medicinal chemistry of curcumin: miniperspective

KM Nelson, JL Dahlin, J Bisson, J Graham… - Journal of medicinal …, 2017 - ACS Publications
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …

Curcumin, the golden spice in treating cardiovascular diseases

H Li, A Sureda, HP Devkota, V Pittalà, D Barreca… - Biotechnology …, 2020 - Elsevier
Cardiovascular diseases (CVDs) cause the largest mortality worldwide, and much attention
has been focused to unravel the mechanisms and optimize the treatment regimens …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - ASPET
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Curcumin: the Indian solid gold

BB Aggarwal, C Sundaram, N Malani… - The molecular targets and …, 2007 - Springer
Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in
the Indian subcontinent, not only for health care but also for the preservation of food and as …

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

P Anand, SG Thomas, AB Kunnumakkara… - Biochemical …, 2008 - Elsevier
Curcumin, a yellow pigment present in the Indian spice turmeric (associated with curry
powder), has been linked with suppression of inflammation; angiogenesis; tumorigenesis; …

Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials

AS Strimpakos, RA Sharma - Antioxidants & redox signaling, 2008 - liebertpub.com
Curcumin is a natural polyphenol used in ancient Asian medicine. Since the first article
referring to the use of curcumin to treat human disease was published in The Lancet in …

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

OI El-Sabbagh, MM Baraka, SM Ibrahim… - European journal of …, 2009 - Elsevier
New N-acetyl (5–8) and N-thiocarbamoyl (9–12) derivatives of 4, 5-dihydropyrazole were
synthesized starting from α, β-unsaturated ketones under the effect of hydrazine hydrate and …

Curcumin and its analogues: potential anticancer agents

DK Agrawal, PK Mishra - Medicinal research reviews, 2010 - Wiley Online Library
This review chronicles the exploration of the curcumin in terms of development of analogues
for the anticancer activity over the last century. Curcumin is a natural phytochemical …

[HTML][HTML] Dietary chalcones with chemopreventive and chemotherapeutic potential

B Orlikova, D Tasdemir, F Golais, M Dicato… - Genes & nutrition, 2011 - Springer
Chalcones are absorbed in the daily diet and appear to be promising cancer
chemopreventive agents. Chalcones represent an important group of the polyphenolic …

[PDF][PDF] Curcumin: A review for health benefits

S Rathore, M Mukim, P Sharma, S Devi, JC Nagar… - Int. J. Res …, 2020 - academia.edu
Curcuma longa (Turmeric) is a popular and widely used Indian rhizomatous medicinal plant
from the family Zingiberaceae. Curcumin, Demethoxycurcumin(DMC), and …