Spread through air spaces (STAS) in lung cancer: a multiple-perspective and update review

M Jia, S Yu, H Gao, PL Sun - Cancer management and research, 2020 - Taylor & Francis
Background Spread through air spaces (STAS) is a spreading phenomenon of lung cancers,
which is defined as tumor cells within air spaces in the lung parenchyma beyond the edge of …

Lobectomy is associated with better outcomes than sublobar resection in spread through air spaces (STAS)-positive T1 lung adenocarcinoma: a propensity score …

T Eguchi, K Kameda, S Lu, MJ Bott, KS Tan… - Journal of thoracic …, 2019 - Elsevier
Introduction Spread through air spaces (STAS) is a form of invasion wherein tumor cells
extend beyond the tumor edge within the lung parenchyma. In lung adenocarcinoma (ADC) …

[HTML][HTML] Significance of tumor spread through air spaces (STAS) in lung cancer from the pathologist perspective

M Mino-Kenudson - Translational lung cancer research, 2020 - ncbi.nlm.nih.gov
Airspace invasion in lung cancer has been known over the last 30 years, but it was only
recently that WHO 2015 formally recognized it as a mechanism of invasion with the …

[HTML][HTML] Tumor spread through air spaces (STAS): prognostic significance of grading in non-small cell lung cancer

YB Han, H Kim, M Mino-Kenudson, S Cho, HJ Kwon… - Modern Pathology, 2021 - Elsevier
Tumor spread through air spaces (STAS) is an invasive pattern of lung cancer that was
recently described. In this study, we investigated the association between the extent of STAS …

Spread through air spaces (STAS) is prognostic in atypical carcinoid, large cell neuroendocrine carcinoma, and small cell carcinoma of the lung

RG Aly, N Rekhtman, X Li, Y Takahashi… - Journal of Thoracic …, 2019 - Elsevier
Introduction Tumor spread through air spaces (STAS) has prognostic significance in lung
adenocarcinoma and squamous cell carcinoma. We sought to investigate the prognostic …

Tumor spread through air spaces is a predictor of occult lymph node metastasis in clinical stage IA lung adenocarcinoma

RG Vaghjiani, Y Takahashi, T Eguchi, S Lu… - Journal of Thoracic …, 2020 - Elsevier
Introduction In patients with stage IA lung adenocarcinoma (ADC), sublobar resection and
tumor spread through air spaces (STAS) are associated with high rates of locoregional …

The evolving concept of complete resection in lung cancer surgery

R Rami-Porta - Cancers, 2021 - mdpi.com
Simple Summary In the surgical treatment of lung cancer, the complete removal of the
portion of the lung where the cancer is and of the involved adjacent structures is of …

Prognostic impact of tumor spread through air spaces for T2aN0 stage IB non‐small cell lung cancer

Z Chen, X Wu, T Fang, Z Ge, J Liu, Q Wu… - Cancer …, 2023 - Wiley Online Library
Background Spread through air spaces (STAS) is a pattern of invasion recently identified in
non‐small cell lung cancer (NSCLC), with a poor prognosis. However, the predictive impact …

The role of spread through air spaces (STAS) in lung adenocarcinoma prognosis and therapeutic decision making

MI Toki, K Harrington, KN Syrigos - Lung Cancer, 2020 - Elsevier
Spread through air spaces (STAS) was included as a novel pattern of invasion in lung
adenocarcinoma by the World Health Organization in 2015. Since then, multiple studies …

Spread through air spaces (STAS): a new pathologic morphology in lung cancer

K Ma, C Zhan, S Wang, Y Shi, W Jiang, Q Wang - Clinical Lung Cancer, 2019 - Elsevier
Abstract In 2015, the World Health Organization classification of lung cancer proposed the
concept of spread through air spaces (STAS) as a new pattern of invasion in lung …