Cachexia is a severe complication of cancer that adversely affects the course of the disease,
with currently no effective treatments. It is characterized by a progressive atrophy of skeletal …

Research about heart failure (HF) has made major progress in the last years. We give here
an update on the most recent findings. Landmark trials have established new treatments for …

Skeletal muscle and brown adipose tissue (BAT) are functionally linked, as exercise
increases browning via secretion of myokines. It is unknown whether BAT affects muscle …

Sarcopenia is primarily characterized by skeletal muscle disturbances such as loss of
muscle mass, quality, strength, and physical performance. It is commonly seen in elderly …

Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Patients suffering from chronic heart failure (CHF) show an increased prevalence (~ 20% in
elderly CHF patients) of loss of muscle mass and muscle function (ie sarcopenia) compared …

Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer
patients. It manifests especially with energy and mitochondrial metabolism aberrations that …

Cachexia is a wasting syndrome characterized by devastating skeletal muscle atrophy that
dramatically increases mortality in various diseases, most notably in cancer patients with a …

Aim Loss of skeletal muscle mass is a common clinical finding in cancer patients. The
purpose of this meta‐analysis and systematic review was to quantify the effect of doxorubicin …

Cancer cachexia is a complex multi‐organ catabolic syndrome that reduces mobility,
increases fatigue, decreases the efficiency of therapeutic strategies, diminishes the quality of …