HS appears to be a well-organised molecule with a domain structure that is apparently
unique amongst the GAG family (Gallagher, 1989). Further refinements in sequence …

Cell walls of brown algae are complex supramolecular assemblies containing various
original, sulfated, and carboxylated polysaccharides. Among these, the major marine …

Complex polysaccharides, glycosaminoglycans (GAGs), are a class of ubiquitous
macromolecules exhibiting a wide range of biological functions. They are widely distributed …

Abstract Structure and anticancer activity of fucoidan from Sargassum horneri and from
products of its enzymatic transformation were investigated. A gene that encodes …

Pseudomonas aeruginosa alginate was purified and characterized in terms of uronic acid,
carbohydrate and protein content, as well as by infra-red spectroscopy and gel …

Oligomeric and polymeric fragments of glycosaminoglycans may be separated for rapid
analysis by electrophoresis through a 10% polyacrylamide matrix. A ladder-like series of …

Activated phagocytes release the haem enzyme MPO (myeloperoxidase) and also generate
superoxide radicals (O2•−), and hence H2O2, via an oxidative burst. Reaction of MPO with …

Chondroitin sulfate was administered orally to six healthy volunteers, six patients with
rheumatoid arthritis and six patients with osteoarthritis. Blood was collected at intervals …

Plasmodium falciparum infection during pregnancy results in the accumulation of infected
red blood cells (IRBCs) in the placenta, leading to poor pregnancy outcome. In the …

Myeloperoxidase released from activated phagocytes reacts with H2O2 in the presence of
chloride ions to give hypochlorous acid. This oxidant has been implicated in the …