Fluorescent molecular rotors for viscosity sensors

SC Lee, J Heo, HC Woo, JA Lee… - … A European Journal, 2018 - Wiley Online Library
Fluorescent molecular rotors (FMRs) can act as viscosity sensors in various media including
subcellular organelles and microfluidic channels. In FMRs, the rotation of rotators connected …

Molecular rotors: what lies behind the high sensitivity of the thioflavin-T fluorescent marker

N Amdursky, Y Erez, D Huppert - Accounts of chemical research, 2012 - ACS Publications
Thioflavin-T (ThT) can bind to amyloid fibrils and is frequently used as a fluo-rescent marker
for in vitro biomedical assays of the potency of inhibitors for amyloid-related diseases, such …

Revisiting thioflavin T (ThT) fluorescence as a marker of protein fibrillation–The prominent role of electrostatic interactions

E Arad, H Green, R Jelinek, H Rapaport - Journal of colloid and interface …, 2020 - Elsevier
Thioflavin T (ThT), a benzothiazole-based fluorophore, is a prominent dye widely employed
for monitoring amyloid fibril assembly. Despite the near-universal presumption that ThT …

Binding of Congo red to amyloid protofibrils of the Alzheimer Aβ9–40 peptide probed by molecular dynamics simulations

C Wu, J Scott, JE Shea - Biophysical journal, 2012 - cell.com
Congo red (CR) is a commonly used histological amyloid dye and a weak amyloid inhibitor.
There is currently no experimentally available structure of CR bound to an amyloid fibril and …

Harnessing intramolecular rotation to enhance two‐photon imaging of Aβ plaques through minimizing background fluorescence

J Shin, P Verwilst, H Choi, S Kang, J Han… - Angewandte …, 2019 - Wiley Online Library
The aggregation of amyloid beta (Aβ) proteins in senile plaques is a critical event during the
development of Alzheimer's disease, and the postmortem detection of Aβ‐rich …

Controlling the fluorescence quantum yields of benzothiazole-difluoroborates by optimal substitution

P Rybczyński, MHE Bousquet… - Chemical …, 2022 - pubs.rsc.org
Precise tuning of the fluorescence quantum yield, vital for countless applications of
fluorophores, remains exceptionally challenging due to numerous factors affecting energy …

Photophysical study of Thioflavin T as fluorescence marker of amyloid fibrils

S Freire, MH de Araujo, W Al-Soufi, M Novo - Dyes and Pigments, 2014 - Elsevier
Thioflavin T is a highly sensitive fluorescent marker of amyloid fibrils that has been widely
used for in vitro biomedical assays. However, neither its complex photophysical behavior …

Molecular Rotor-Based Fluorescent Probe for Selective Recognition of Hybrid G-Quadruplex and as a K+ Sensor

L Liu, Y Shao, J Peng, C Huang, H Liu… - Analytical …, 2014 - ACS Publications
This work demonstrates the significant fluorescence enhancement of thioflavin T (ThT) when
binding to G-quadruplexes possessing hybrid structures by using UV–vis absorption …

Ultrasensitive and highly selective detection of strontium ions

L Feng, H Wang, T Liu, T Feng, M Cao, J Zhang… - Nature …, 2023 - nature.com
Strontium-90 is one of the most frequently released radioactive products in waste
discharged from nuclear reactors. With a long half-life and chemical similarity to calcium, this …

Thioflavin-T: A quantum yield-based molecular viscometer for glycerol–monohydroxy alcohol mixtures

P Mukherjee, S Ganai - ACS omega, 2023 - ACS Publications
Molecular rotor dye thioflavin T (ThT) is almost nonfluorescent in low-viscosity solvents but
highly fluorescent when bound to amyloid fibrils. This unique property arises from the …