Sphingolipids and lipid rafts: Novel concepts and methods of analysis

E Bieberich - Chemistry and physics of lipids, 2018 - Elsevier
About twenty years ago, the functional lipid raft model of the plasma membrane was
published. It took into account decades of research showing that cellular membranes are not …

Role of reactive oxygen and nitrogen species in the vascular responses to inflammation

PR Kvietys, DN Granger - Free Radical Biology and Medicine, 2012 - Elsevier
Inflammation is a complex and potentially life-threatening condition that involves the
participation of a variety of chemical mediators, signaling pathways, and cell types. The …

Overexpression or Deletion of Ergosterol Biosynthesis Genes Alters Doubling Time, Response to Stress Agents, and Drug Susceptibility in Saccharomyces cerevisiae

S Bhattacharya, BD Esquivel, TC White - MBio, 2018 - Am Soc Microbiol
Ergosterol (ERG) is a critical sterol in the cell membranes of fungi, and its biosynthesis is
tightly regulated by 25 known enzymes along the ERG production pathway. The effects of …

Protein folding and quality control in the ER

K Araki, K Nagata - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
The endoplasmic reticulum (ER) uses an elaborate surveillance system called the ER
quality control (ERQC) system. The ERQC facilitates folding and modification of secretory …

Mechanical stretch activates piezo1 in caveolae of alveolar type I cells to trigger ATP release and paracrine stimulation of surfactant secretion from alveolar type II cells

K Diem, M Fauler, G Fois, A Hellmann… - The FASEB …, 2020 - Wiley Online Library
Secretion of pulmonary surfactant in the alveoli of the lungs is essential to maintain lung
function. Stretching of alveoli during lung inflation is the main trigger for surfactant secretion …

Plasmalogens the neglected regulatory and scavenging lipid species

S Wallner, G Schmitz - Chemistry and physics of lipids, 2011 - Elsevier
Plasmalogens are a class of phospholipids carrying a vinyl ether bond in sn-1 and an ester
bond in sn-2 position of the glycerol backbone. Although they are widespread in all tissues …

Role of oleic acid in immune system; mechanism of action; a review

C Carrillo Pérez, MM Cavia Camarero… - … , 2012, v. 27, n. 4 (julio …, 2012 - riubu.ubu.es
Introduction: Although n-3 polyunsaturated fatty acids have been widely described as
antiinflammatory fats, little is known about the role of oleic acid in immune system. Aim: The …

Contribution and regulation of TRPC channels in store-operated Ca2+ entry

KT Cheng, HL Ong, X Liu, IS Ambudkar - Current topics in membranes, 2013 - Elsevier
Store-operated calcium entry (SOCE) is activated in response to depletion of the
endoplasmic reticulum-Ca 2+ stores following stimulation of plasma membrane receptors …

Caveolae, caveolins, cavins, and endothelial cell function: new insights

G Sowa - Frontiers in physiology, 2012 - frontiersin.org
Caveolae are cholesterol and glycosphingolipid-rich flask-shaped invaginations of the
plasma membrane which are particularly abundant in vascular endothelium and present in …

The role of nutrients in protecting mitochondrial function and neurotransmitter signaling: implications for the treatment of depression, PTSD, and suicidal behaviors

J Du, M Zhu, H Bao, B Li, Y Dong, C Xiao… - Critical reviews in …, 2016 - Taylor & Francis
Numerous studies have linked severe stress to the development of major depressive
disorder (MDD) and suicidal behaviors. Furthermore, recent preclinical studies from our …