AI powered quantification of nuclear morphology in cancers enables prediction of genome instability and prognosis

J Abel, S Jain, D Rajan, H Padigela, K Leidal… - npj Precision …, 2024 - nature.com
While alterations in nucleus size, shape, and color are ubiquitous in cancer, comprehensive
quantification of nuclear morphology across a whole-slide histologic image remains a …

[PDF][PDF] Cell-type-specific nuclear morphology predicts genomic instability and prognosis in multiple cancer types

J Abel, S Jain, D Rajan, H Padigela, K Leidal… - bioRxiv, 2023 - scholar.archive.org
Background: Altered nuclei are ubiquitous in cancer, with changes in nuclear size, shape,
and coloration accompanying cancer progression. However, comprehensive quantification …

Deep-learning quantified cell-type-specific nuclear morphology predicts genomic instability and prognosis in multiple cancer types

J Abel, S Jain, D Rajan, H Padigela, K Leidal… - bioRxiv, 2023 - biorxiv.org
Background Altered nuclei are ubiquitous in cancer, with changes in nuclear size, shape,
and coloration accompanying cancer progression. However, comprehensive quantification …