In just over two decades since the discovery of the first microRNA (miRNA), the field of
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …

Forkhead box O (FOXO) transcription factors regulate diverse biological processes, affecting
development, metabolism, stem cell maintenance and longevity. They have also been …

The Cyclin-dependent kinase (CDK) class of serine/threonine kinases has crucial roles in
the regulation of cell cycle transition and is mainly involved in the pathogenesis of cancers …

The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the
essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell …

Ovarian cancer is a gynecological cancer with high mortality and a heterogeneous nature
which complicates its early detection and primary prevention. Numerous studies have …

Human cancers are characterized by a number of hallmarks, including sustained
proliferative signaling, evasion of growth suppressors, activated invasion and metastasis …

Simple Summary Ovarian cancer is a lethal disease in women with a 10-year survival rate
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …

Ovarian cancer is the most lethal of malignant gynecological tumors. Its lethality may be due
to difficulties in detecting it at an early stage and lack of effective treatments for patients with …

The aberrant expression of microRNAs (miRNAs) has emerged as an important hallmark of
cancer. However, the molecular mechanisms underlying the changes in miRNA expression …

Context: MicroRNAs (miRNAs) are small, noncoding RNAs that negatively regulate gene
expression post-transcriptionally. Whether differently expressed miRNAs contribute to …