Managing fatigue in patients with paroxysmal nocturnal hemoglobinuria: A patient-focused perspective

B Fattizzo, F Cavallaro, EN Oliva… - Journal of Blood …, 2022 - Taylor & Francis
The most frequently reported symptom in patients with paroxysmal nocturnal
hemoglobinuria (PNH), a disease characterized by complement mediated hemolysis and …

Current opinions on the clinical utility of ravulizumab for the treatment of paroxysmal nocturnal hemoglobinuria

C Gurnari, I Nautiyal, S Pagliuca - Therapeutics and Clinical Risk …, 2021 - Taylor & Francis
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder of hematopoietic stem cells
genetically defined by the acquisition of somatic mutations in the X-linked …

阵发性睡眠性血红蛋白尿症多学科诊疗专家共识(2024)

陈苗, 杨辰, 刘紫薇, 曹玮, 张波, 刘鑫, 李景南… - 协和医学 …, 2024 - xhyxzz.pumch.cn
阵发性睡眠性血红蛋白尿症(paroxysmal nocturnal hemoglobinuria, PNH)
是一种由于磷脂酰肌醇聚糖A 基因突变引起细胞膜上锚链蛋白糖基磷脂酰肌醇 …

Paroxysmal nocturnal hemoglobinuria-related thrombosis in the era of novel therapies: a 2043 patient/years analysis

C Gurnari, H Awada, S Pagliuca, D Dima, F Ullah… - Blood, 2024 - Elsevier
Thrombophilia is one of the principal features of paroxysmal nocturnal hemoglobinuria
(PNH) and constitutes the main cause of disease morbidity/mortality. Anti-complement …

Etiology of the Budd-Chiari syndrome

M Lai - UpToDate, Chopra, S (Ed), UpToDate, Robson, K …, 2020 - uptodate.com
The Budd-Chiari syndrome can be defined as any pathophysiologic process that results in
an interruption or diminution of the normal flow of blood out of the liver [1, 2]. However, as …

Expert Consensus of Multidisciplinary Diagnosis and Treatment for Paroxysmal Nocturnal Hemoglobinuria (2024)

C Miao, Y Chen, LIU Ziwei, CAO Wei, Z Bo… - Medical Journal of …, 2024 - xhyxzz.pumch.cn
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal hematopoietic stem cell
disease caused by abnormal expression of glycosylphosphatidylinositol (GPI) on the cell …