The present review “Iron Catalysis in Organic Synthesis” covers the literature until the end of
June 2014 and represents a comprehensive update of a previous article published by Bolm …

Screening of small-molecule libraries is a productive method for identifying both chemical
probes of disease-related targets and potential starting points for drug discovery. In this …

With the ever-present need for novel asymmetric methodologies in organic synthesis to
allow chemists to access enantiopure compounds, so too is there a need for new chiral …

Reactive intermediates as recognized chemical entities date back for over a century, and
among the earliest examples were simple free radicals, as identified in 1879, when it was …

Serine hydrolases perform crucial roles in many biological processes, and several of these
enzymes are targets of approved drugs for indications such as type 2 diabetes, Alzheimer's …

Electrophilic addition of alkenes is a textbook reaction that plays a pivotal role in organic
chemistry. In the past decades, catalytic asymmetric variants of this important type of reaction …

Asymmetric catalysis holds a prominent position among the important developments in
chemistry during the 20th century. This was acknowledged by the 2001 Nobel Prize in …

Tetramisole promotes the catalytic asymmetric intramolecular Michael addition−
lactonization of a variety of enone acids, giving carbo-and heterocyclic products with high …

[4 + 2] Cycloaddition of Ketenes with Nâ•’Benzoyldiazenes Catalyzed by Nâ•’Heterocyclic
Carbenes. Page 1 ChemInform 2009, 40, issue 19 © 2009 Wiley-VCH Verlag GmbH & Co …

A straightforward synthesis of optically active trifluoromethyl dihydropyranones and
spirocyclic oxindole‐dihydropyranones has been realized by the chiral N‐heterocyclic …