Potent acetylcholinesterase inhibitors: potential drugs for Alzheimer's disease
H Akıncıoğlu, İ Gülçin - Mini reviews in medicinal chemistry, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is one of the cognitive or memory-related impairments occurring
with advancing age. Since its exact mechanism is not known, the full therapy has still not …
with advancing age. Since its exact mechanism is not known, the full therapy has still not …
Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibitors
S Burmaoglu, AO Yilmaz, MF Polat, R Kaya, İ Gulcin… - Bioorganic …, 2019 - Elsevier
A novel class of fluoro-substituted tris-chalcones derivatives (5a-5i) was synthesized from
phloroglucinol and corresponding benzaldehydes. A three step synthesis method was …
phloroglucinol and corresponding benzaldehydes. A three step synthesis method was …
[HTML][HTML] Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS
Many chronic diseases such as diabetes and Alzheimer's disease are related to the type
and quality of foods, which are consumed. Particularly, various plant origin products are …
and quality of foods, which are consumed. Particularly, various plant origin products are …
Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes
In this study, a series of novel bis-thiomethylcyclohexanone compounds (3a–3j) were
synthesized by the addition of thio-Michael to the bis-chalcones under mild reaction …
synthesized by the addition of thio-Michael to the bis-chalcones under mild reaction …
Synthesis, characterization, molecular docking, and biological activities of coumarin–1, 2, 3‐triazole‐acetamide hybrid derivatives
N Sepehri, M Mohammadi‐Khanaposhtani… - Archiv der …, 2020 - Wiley Online Library
Coumarins and their derivatives are receiving increasing attention due to numerous
biochemical and pharmacological applications. In this study, a series of novel coumarin–1 …
biochemical and pharmacological applications. In this study, a series of novel coumarin–1 …
Imidazolinium chloride salts bearing wingtip groups: Synthesis, molecular docking and metabolic enzymes inhibition
A series of symmetrical imidazolinium chloride salts bearing secondary N-alkyl substituents
were synthesized in good yield by the reaction of N, N′-dialkylethane-1, 2-diamines and …
were synthesized in good yield by the reaction of N, N′-dialkylethane-1, 2-diamines and …
Novel morpholine liganded Pd-based N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure, antidiabetic and anticholinergic properties
This study involves the synthesis of novel N-heterocyclic carbene (NHC) PdX 2 (morpholine)
complexes (1a–i). These Pd-based complexes are synthesized from pyridine enhanced …
complexes (1a–i). These Pd-based complexes are synthesized from pyridine enhanced …
Cholinesterases, carbonic anhydrase inhibitory properties and in silico studies of novel substituted benzylamines derived from dihydrochalcones
A series of novel urea, sulfamide and N, N-dipropargyl substituted benzylamines were
synthesized from dihydrochalcones. The synthesized compounds were evaluated for their …
synthesized from dihydrochalcones. The synthesized compounds were evaluated for their …
The synthesis, carbonic anhydrase and acetylcholinesterase inhibition effects of sulfonyl chloride moiety containing oxazolidinones using an intramolecular aza …
Oxazolidinones are used as various potent antibiotics, in organisms it acts as a protein
synthesis inhibitor, focusing on an initial stage that encompasses the tRNA binding process …
synthesis inhibitor, focusing on an initial stage that encompasses the tRNA binding process …
Synthesis of oxazolidinone from enantiomerically enriched allylic alcohols and determination of their molecular docking and biologic activities
Enantioselective synthesis of functionalized cyclic allylic alcohols via kinetic resolution in
transesterifcation with different lipase enzymes has been developed. The influence of the …
transesterifcation with different lipase enzymes has been developed. The influence of the …