Two decades have passed since the development of the first calcium indicator based on the
green fluorescent protein (GFP) and the principle of Förster resonance energy transfer …

The small GTPases of the Rho-family (Rho-family GTPases) have various physiological
functions, including cytoskeletal regulation, cell polarity establishment, cell proliferation and …

The Neural Calcium Sensor1 (NCS1) is a crucial protein that binds to Ca2+ and is believed
to play a role in regulating tumor invasion and cell proliferation. However, the role of NCS1 …

Biosensors based on the principle of Förster (or fluorescence) resonance energy transfer
(FRET) have been developed to visualize spatio-temporal dynamics of signalling molecules …

Glioblastoma (GBM) is the most common and deadly malignant brain cancer of glial cell
origin, with a median patient survival of less than 20 months. Transcription factors FOXG 1 …

Astrogliosis (ie glial scar), which is comprised primarily of proliferated astrocytes at the
lesion site and migrated astrocytes from neighboring regions, is one of the key reactions in …

Förster (or fluorescence) resonance energy transfer (FRET) is a nonradiative energy transfer
process between two fluorophores located in close proximity to each other. To date, a variety …

Cancer cells are able to survive under conditions that cause endoplasmic reticulum stress
(ER-stress), and can adapt to this stress by upregulating cell-survival signalling pathways …

Although the 5-year survival rate of osteosarcoma (OS) has risen to~ 60-70%, a substantial
portion of patients still respond poorly to chemotherapy and have a high risk of relapse or …

Abstract Polypeptide‑N‑acetyl‑galactosaminlytransferase 7 (GALNT7), a member of the
GalNAc‑transferase family, has not been previously evaluated as a prognostic factor of …