A review of brain regions and associated post-concussion symptoms

E Danielli, N Simard, CA DeMatteo… - Frontiers in …, 2023 - frontiersin.org
The human brain is an exceptionally complex organ that is comprised of billions of neurons.
Therefore, when a traumatic event such as a concussion occurs, somatic, cognitive …

T1 and T2 weighted lesions and cognition in multiple Sclerosis: A systematic review and meta-analysis

F Nabizadeh, K Pirahesh, M Azami… - Journal of Clinical …, 2024 - Elsevier
Background Considering the different results regarding the correlation between Magnetic
Resonance Imaging (MRI) structural measures and cognitive dysfunction in patients with …

[HTML][HTML] Effects of arketamine on depression-like behaviors and demyelination in mice exposed to chronic restrain stress: A role of transforming growth factor-β1

D Xu, G Liu, M Zhao, X Wan, Y Qu, R Murayama… - Journal of Affective …, 2024 - Elsevier
Background Chronic restrain stress (CRS) induces depression-like behaviors and
demyelination in the brain; however, the relationship between these depression-like …

CSF Parvalbumin levels at multiple sclerosis diagnosis Predict future worse cognition, physical disability, fatigue, and gray matter damage

S Ziccardi, A Tamanti, C Ruggieri… - Neurology …, 2024 - neurology.org
Background and Objectives Cognitive impairment (CI) in multiple sclerosis (MS) is frequent
and determined by a complex interplay between inflammatory and neurodegenerative …

[HTML][HTML] Transforming growth factor-β1 mediates the beneficial effects of arketamine on demyelination and remyelination in the brains of cuprizone-treated mice

M Zhao, T Zhu, D Xu, X Wan, G Liu, R Murayama… - European Journal of …, 2024 - Elsevier
The novel antidepressant arketamine, the (R)-enantiomer of ketamine, has been shown to
ameliorate demyelination and facilitate remyelination in the brains of cuprizone (CPZ) …

Cognitive sparing in proton versus photon radiotherapy for pediatric brain tumor is associated with white matter integrity: an exploratory study

LE Mash, LS Kahalley, KP Raghubar… - Cancers, 2023 - mdpi.com
Simple Summary Research has shown that children who undergo radiotherapy for brain
tumors are at risk for long-term changes in both their thinking and brain structure. Compared …

Arketamine alleviates cognitive impairments and demyelination in mice with postoperative cognitive dysfunction via TGF-β1 activation

TT Zhu, MM Zhao, D Xu, Y Cai, G Liu… - Progress in Neuro …, 2025 - Elsevier
Postoperative cognitive dysfunction (POCD) is characterized by a decline in cognitive
functions, including memory, attention, and executive abilities, following surgery, with no …

The association between white matter tract structural connectivity and information processing speed in relapsing-remitting multiple sclerosis

M Chylińska, B Karaszewski, J Komendziński… - Neurological …, 2023 - Springer
Background Information processing speed (IPS) deterioration is common in relapsing-
remitting multiple sclerosis (RRMS) patients and might severely affect quality of life and …

[HTML][HTML] Microbiome depletion by broad-spectrum antibiotics does not influence demyelination and remyelination in cuprizone-treated mice

R Murayama, G Liu, M Zhao, D Xu, T Zhu, Y Cai… - Pharmacology …, 2025 - Elsevier
Demyelination in the central nervous system (CNS) is a feature of various psychiatric and
neurological disorders. Emerging evidence suggests that the gut-brain axis may play a …

Performance in information processing speed is associated with parietal white matter tract integrity in multiple sclerosis

M Grothe, K Jochem, S Strauss, S Langner… - Frontiers in …, 2022 - frontiersin.org
Background The Symbol Digit Modalities Test (SDMT) is most frequently used to test
processing speed in patients with multiple sclerosis (MS). Functional imaging studies …