Digestive system cancer tumors are one of the major causes of cancer-related fatalities; the
vast majority of them are colorectal or gastric malignancies. Epidemiological evidence …

Compounds with the structure RSSR, where the R group can be alkyl, vinyl or aryl are
termed disulfides and symmetrical disufides when the R groups are the same …

We identified four anti-inflammatory sulfur-containing compounds from garlic, and their
chemical structures were identified as Z-and E-ajoene and oxidized sulfonyl derivatives of …

cis-1, 2-Cyclohexanediol (L3) has been shown to be an efficient and versatile bidentate O-
donor ligand that provides a highly active Cu-catalytic system. It was more effective than …

Garlic has been used throughout the centuries to treat infections, heart disease, and cancer.
Ajoene is one of the main compounds formed from heating crushed garlic as a mixture of E …

The neuroprotective effects of two isomers (Z-and E-) of ajoene, a major compound in oil-
macerated garlic products, against ischemic damage were investigated in the gerbil …

The organosulfur compound ajoene derived from the rearrangement of allicin found in
crushed garlic can inhibit the proliferation of tumour cells by inducing G2/M cell cycle arrest …

Hepatic steatosis, a hepatic component of metabolic syndrome, is common and may
progress to steatohepatitis and cirrhosis. The liver X receptor-α (LXRα)-sterol regulatory …

Ajoene is a natural allylsulfur compound found in crushed garlic that arrests growth and
induces apoptosis in cancer cells. To gain mechanistic insights into the cytotoxicity of ajoene …

We describe a short total synthesis of ajoene, a major biologically active constituent of garlic.
The instability of allicin as the only other known alternative starting material has led to the …