Diabetic macular edema: current understanding, molecular mechanisms and therapeutic implications

J Zhang, J Zhang, C Zhang, J Zhang, L Gu, D Luo… - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), with increasing incidence, is the major cause of vision loss and
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …

[HTML][HTML] Mechanisms of macular edema: beyond the surface

A Daruich, A Matet, A Moulin, L Kowalczuk… - Progress in retinal and …, 2018 - Elsevier
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma

Y Miao, GL Zhao, S Cheng, Z Wang, XL Yang - Progress in retinal and eye …, 2023 - Elsevier
Elevation of intraocular pressure (IOP) is a major risk factor for neurodegeneration in
glaucoma. Glial cells, which play an important role in normal functioning of retinal neurons …

Astrocytes in the regulation of cerebrovascular functions

M Cohen‐Salmon, L Slaoui, N Mazaré, A Gilbert… - Glia, 2021 - Wiley Online Library
Astrocytes are the most numerous type of neuroglia in the brain and have a predominant
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …

[HTML][HTML] The role of Müller cells in diabetic macular edema

D Lai, Y Wu, C Shao, Q Qiu - Investigative Ophthalmology & …, 2023 - tvst.arvojournals.org
Diabetic macular edema (DME) is a common complication of diabetic retinopathy and is the
leading cause of vision loss in diabetic patients. Various factors, such as metabolic disorders …

Dystrophin Dp71: the smallest but multifunctional product of the Duchenne muscular dystrophy gene

R Tadayoni, A Rendon, LE Soria-Jasso… - Molecular …, 2012 - Springer
Dystrophin Dp71 is expressed in all tissues, with the exception of skeletal muscle, and is the
main Duchenne muscular dystrophy (DMD) gene product in brain. As full-length dystrophin …

Astrogliosis and impaired aquaporin‐4 and dystrophin systems in idiopathic normal pressure hydrocephalus

PK Eide, HA Hansson - Neuropathology and Applied …, 2018 - Wiley Online Library
Aims Idiopathic normal pressure hydrocephalus (iNPH) is one subtype of dementia that may
improve following drainage of cerebrospinal fluid (CSF). This prospective observational …

Microvascular destabilization and intricated network of the cytokines in diabetic retinopathy: from the perspective of cellular and molecular components

X Sheng, C Zhang, J Zhao, J Xu, P Zhang, Q Ding… - Cell & Bioscience, 2024 - Springer
Microvascular destabilization is the primary cause of the inner blood-retinal barrier (iBRB)
breakdown and increased vascular leakage in diabetic retinopathy (DR). Microvascular …

Dystrophin short product, Dp71, interacts with AQP4 and Kir4. 1 channels in the mouse cerebellar glial cells in contrast to Dp427 at inhibitory postsynapses in the …

T Fujimoto, K Stam, T Yaoi, K Nakano, T Arai… - Molecular …, 2023 - Springer
Dystrophin is the causative gene for Duchenne and Becker muscular dystrophy (DMD/BMD),
and it produces full-length and short dystrophin, Dp427 and Dp71, respectively, in the brain …

Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies

C Perronnet, C Vaillend - BioMed Research International, 2010 - Wiley Online Library
Two decades of molecular, cellular, and functional studies considerably increased our
understanding of dystrophins function and unveiled the complex etiology of the cognitive …