The link between cancer and inflammation is specific transcription factors that once activated
have the capacity to enhance expression of genes that are common to both the regulation …

Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades
local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment …

The cyclooxygenase-2 (COX-2) is a potent enzyme that converts arachidonic acid to
prostaglandins (PG), including PGE2, a key mediator of inflammation and angiogenesis …

The precise role of transforming growth factor (TGF)-β signaling in head and neck squamous
cell carcinoma (SCC) is not yet fully understood. Here, we report generation of an inducible …

Oral carcinogenesis, a multistep process with multifaceted etiology, arises due to
accumulation of heterogeneous genetic changes in the genes involved in the basic cellular …

OBJECTIVE: Oral lichenoid disease (OLD) includes a number of chronic inflammatory
processes including oral lichen planus (OLP) and oral lichenoid lesions (OLL) with …

Background: Many evidences showed that cyclooxygenase-2 (COX-2), an enzyme that
catalyzes the synthesis of prostaglandins, has an important role in carcinogenesis. It has …

Background An accurate system for predicting the survival of patients with oral squamous
cell carcinoma (OSCC) will be useful for deciding appropriate therapies. The prediction …

Objective This study aimed to evaluate the presence of human papillomavirus (HPV) and
Epstein–Barr virus (EBV) and the expression of p53, p16, E‐cadherin, COX‐2, MLH1, and …

In this study, we investigated the chemopreventive efficacy of usnic acid (UA), an effective
secondary metabolite component of lichens, against 7, 12‐dimethylbenz [a] anthracene …