Cellular basis of organotin (IV) derivatives as anticancer metallodrugs: A review

SN Syed Annuar, NF Kamaludin, N Awang… - Frontiers in …, 2021 - frontiersin.org
Organotin (IV) compounds have wide applications in industrial and agricultural fields owing
to their ability to act as poly (vinyl chloride) stabilizers and catalytic agents as well as their …

Organotin polymers as anticancer and antiviral agents

CE Carraher Jr, MR Roner - Journal of Organometallic Chemistry, 2014 - Elsevier
Organotin polymers are easily synthesized employing interfacial polymerization systems
involving the reaction of difunctional Lewis bases and organotin halides. A wide variety of …

Organotin (IV) dithiocarbamate compounds as anticancer agents: a review of syntheses and cytotoxicity studies

NA Abd Aziz, N Awang, KM Chan, NF Kamaludin… - Molecules, 2023 - mdpi.com
Organotin (IV) dithiocarbamate has recently received attention as a therapeutic agent
among organotin (IV) compounds. The individual properties of the organotin (IV) and …

Series of organotin (IV) compounds with different dithiocarbamate ligands induced cytotoxicity, apoptosis and cell cycle arrest on Jurkat E6. 1, T acute lymphoblastic …

NR Rasli, A Hamid, N Awang, NF Kamaludin - Molecules, 2023 - mdpi.com
The discovery of cisplatin has influenced scientists to study the anticancer properties of other
metal complexes. Organotin (IV) dithiocarbamate compounds are gaining attention as …

Synthesis, structural characterization, and anticancer activity of a monobenzyltin compound against MCF-7 breast cancer cells

S Fani, B Kamalidehghan, KM Lo… - Drug design …, 2015 - Taylor & Francis
A new monoorganotin Schiff base compound,[N-(3, 5-dichloro-2-oxidobenzylidene)-4-
chlorobenzyhydrazidato](o-methylbenzyl) aquatin (IV) chloride,(compound C1), was …

Triphenyltin (IV) dithiocarbamate compound induces genotoxicity and cytotoxicity in K562 human erythroleukemia cells primarily via mitochondria-mediated apoptosis

SNS Annuar, NF Kamaludin, N Awang… - Food and Chemical …, 2022 - Elsevier
The novel di-and triphenyltin (IV) dithiocarbamate compounds represented as R n SnL 2
(where R= C 4 H 9, C 6 H 5; n= 2, 3; L= N, N-dithiocarbamate), Ph 2 Sn (N, N …

Synthesis, characterization and crystal structure of organotin (IV) N-butyl-N-phenyldithiocarbamate compounds and their cytotoxicity in human leukemia cell lines.

NF Kamaludin, N Awang, I Baba, A Hamid… - Pakistan Journal of …, 2013 - europepmc.org
Organotin complexes are recognized as the biologically active compounds in inducing
cancerous cells death at very low doses. To date, organotin compounds currently appear …

Triorganotin (IV) carboxylates as potential anticancer agents: Their synthesis, physiochemical characterization, and cytotoxic activity against HeLa and MCF‐7 cancer …

N Uddin, F Rashid, A Haider, SA Tirmizi… - Applied …, 2021 - Wiley Online Library
Three triorganotin (IV) cyclopentane carboxylates were synthesized and structurally
characterized by in solid state by Fourier‐transform infrared spectroscopy and single crystal …

Monobenzyltin complex C1 induces apoptosis in MCF-7 breast cancer cells through the intrinsic signaling pathway and through the targeting of MCF-7-derived breast …

S Fani, F Dehghan, H Karimian, K Mun Lo… - PLoS …, 2016 - journals.plos.org
Monobenzyltin Schiff base complex,[N-(3, 5-dichloro-2-oxidobenzylidene)-4-
chlorobenzyhydrazidato](o-methylbenzyl) aquatin (IV) chloride, C1, is an organotin non …

Antibacterial and molecular study of thiourea derivative ligand and its Dimethyltin (IV) complex with the superior of its Copper (II) complex as a hepatocellular …

SS Hassan, RN Shallan, MM Salama - Journal of Organometallic Chemistry, 2020 - Elsevier
benzoyl (1, 2, 4-triazol-3-yl) thiourea [BTThU] ligand and its [dimethyltin (IV), Pd (II) and Cu
(II)] complexes are synthesized. The complexes are formed in molar ratio Cu (BTThU) 2 …