Osteoarthritis (OA), one of the most common joint diseases, is characterized by fibrosis,
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …

Humans and animals lose tissues and organs due to congenital defects, trauma, and
diseases. The human body has a low regenerative potential as opposed to the urodele …

Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

Connective tissue is one of the four major types of animal tissue and plays essential roles
throughout the human body. Genetic factors, aging, and trauma all contribute to connective …

Current cell-based repair strategies have proven unsuccessful for treating cartilage defects
and osteoarthritic lesions, consequently advances in innovative therapeutics are required …

Clinical treatments for the repair of osteochondral defects (OCD) are merely palliative, not
completely curative, and thus enormously unfulfilled challenges. With the in‐depth studies of …

Articular cartilage defects are prevalent and are potentially involved in the initiation of
osteoarthritis, yet the lack of efficient therapeutic options to treat cartilage defects represents …

Hydrogels have gained intensive interest in biomedical and flexible electronics, and
adhesion of hydrogels to substrates or devices is indispensable in these application …

The field of articular cartilage repair has made significant advances in recent decades; yet
current therapies are generally not evaluated or tested, at the time of pivotal trial, in patients …

Tissue engineering (TE) provides a practicable method for tissue and organ repair or
substitution. As the most important component of TE, a scaffold plays a critical role in …