[HTML][HTML] Antibiotics: conventional therapy and natural compounds with antibacterial activity—a pharmaco-toxicological screening

DF Pancu, A Scurtu, IG Macasoi, D Marti, M Mioc… - Antibiotics, 2021 - mdpi.com
Antibiotics are considered as a cornerstone of modern medicine and their discovery offers
the resolution to the infectious diseases problem. However, the excessive use of antibiotics …

[HTML][HTML] Antibiotic-induced epileptic seizures: mechanisms of action and clinical considerations

P Wanleenuwat, N Suntharampillai, P Iwanowski - Seizure, 2020 - Elsevier
In recent years, there has been growing interest in the development of epileptic seizures as
an adverse effect of antibiotic therapy. The most commonly accepted mechanisms …

[HTML][HTML] Occurrence, risk assessment, and in vitro and in vivo toxicity of antibiotics in surface water in China

C Zhang, Y Chen, S Chen, X Guan, Y Zhong… - … and Environmental Safety, 2023 - Elsevier
Antibiotics have been widely detected in the water environment and thus pose a potential
threat to human health. Although antibiotics have health-promoting properties, whether and …

Antibiotics and the nervous system—which Face of antibiotic therapy is real, dr. Jekyll (neurotoxicity) or mr. Hyde (neuroprotection)?

M Hurkacz, L Dobrek, A Wiela-Hojeńska - Molecules, 2021 - mdpi.com
Antibiotics as antibacterial drugs have saved many lives, but have also become a victim of
their own success. Their widespread abuse reduces their anti-infective effectiveness and …

[HTML][HTML] Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies

SP Cohen, EJ Wang, TL Doshi, L Vase, KA Cawcutt… - BMJ …, 2022 - ncbi.nlm.nih.gov
Throughout human history, infection has been the leading cause of morbidity and mortality,
with pain being one of the cardinal warning signs. However, in a substantial percentage of …

Exploring the impact of gut microbiota and diet on breast cancer risk and progression

NMY Teng, CA Price, AM McKee, LJ Hall… - … journal of cancer, 2021 - Wiley Online Library
There is emerging evidence that resident microbiota communities, that is, the microbiota,
play a key role in cancer outcomes and anticancer responses. Although this has been …

The tale of antibiotics beyond antimicrobials: Expanding horizons

S Yadav, D Shah, P Dalai, R Agrawal-Rajput - Cytokine, 2023 - Elsevier
Antibiotics had proved to be a godsend for mankind since their discovery. They were once
the magical solution to the vexing problem of infection-related deaths. German scientist Paul …

Moringa oleifera leaf extract restored the diameter and epithelium thickness of the seminiferous tubules of rat (Rattus norvegicus) injected with gentamicin

AWP Purnama, LT Suwanti… - Journal of Parasite …, 2022 - repository.unair.ac.id
The purpose of this study was to determine the prevalence of gastrointesatinal parasites in
cats at Surabaya shelter. Eighty two samples of cat feces used in this study were taken from …

Off Target Toxicities and Links with Physicochemical Properties of Medicinal Products, including Antibiotics, Oligonucleotides, Lipid nanoparticles (with cationic and/or …

S Gould, MV Templin - Toxicology Letters, 2023 - Elsevier
Toxicology is an essential part of any drug development plan. Circumnavigating the risk of
failure because of a toxicity issue can be a challenge, and failure in late development is …

The Fabrication of Mechanobactericidal Coating and Its Application in Mechanical Sterilization

C Qing, W Han, H Zeng, P Jin, Y Wang… - Advanced Materials …, 2023 - Wiley Online Library
Bacteria are difficult to be eliminated because of their multi‐drug resistance, which brings
significant threats to public health. Among the antibacterial methods, mechanobactericidal …