Antimicrobial peptides: An alternative to traditional antibiotics

S Ji, F An, T Zhang, M Lou, J Guo, K Liu, Y Zhu… - European Journal of …, 2024 - Elsevier
As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …

Antimicrobial peptides

NSMH Mohaideen, S Vaani, S Hemalatha - Current Pharmacology …, 2023 - Springer
Abstract Purpose of Review The review provides deep understanding on antimicrobial
peptides, properties, mechanisms, role in treating diseases, computational drug design, and …

Designing antimicrobial peptides using deep learning and molecular dynamic simulations

Q Cao, C Ge, X Wang, PJ Harvey… - Briefings in …, 2023 - academic.oup.com
With the emergence of multidrug-resistant bacteria, antimicrobial peptides (AMPs) offer
promising options for replacing traditional antibiotics to treat bacterial infections, but …

Bioactive Molecules from the Innate Immunity of Ascidians and Innovative Methods of Drug Discovery: A Computational Approach Based on Artificial Intelligence

L La Paglia, M Vazzana, M Mauro, A Urso, V Arizza… - Marine Drugs, 2023 - mdpi.com
The study of bioactive molecules of marine origin has created an important bridge between
biological knowledge and its applications in biotechnology and biomedicine. Current studies …

DMAMP: A deep-learning model for detecting antimicrobial peptides and their multi-activities

Q Meng, G Chen, S Zheng, Y Lin, B Liu… - IEEE/ACM …, 2024 - ieeexplore.ieee.org
Due to the broad-spectrum and high-efficiency antibacterial activity, antimicrobial peptides
(AMPs) and their functions have been studied in the field of drug discovery. Using biological …

A novel stacking-based predictor for accurate prediction of antimicrobial peptides

S Kanwal, R Arif, S Ahmed, M Kabir - Journal of Biomolecular …, 2024 - Taylor & Francis
Antimicrobial peptides (AMPs) are gaining acceptance and support as a chief antibiotic
substitute since they boost human immunity. They retain a wide range of actions and have a …

Diff-AMP: tailored designed antimicrobial peptide framework with all-in-one generation, identification, prediction and optimization

R Wang, T Wang, L Zhuo, J Wei, X Fu… - Briefings in …, 2024 - academic.oup.com
Antimicrobial peptides (AMPs), short peptides with diverse functions, effectively target and
combat various organisms. The widespread misuse of chemical antibiotics has led to …

In SilicoDesign and Synthesis of Antifungal Peptides Guided by Quantitative Antifungal Activity

J Zhang, X Sun, H Zhao, X Zhou, Y Zhang… - Journal of Chemical …, 2024 - ACS Publications
Antifungal peptides (AFPs) are emerging as promising candidates for advanced antifungal
therapies because of their broad-spectrum efficacy and reduced resistance development. In …

[PDF][PDF] Computational biology in topical bioactive peptide discovery for cosmeceutical application: a concise review

XH Li, WR Su, FF Wang, K Li, J Zhu, S Zhu… - Biomed Eng …, 2023 - tmrjournals.com
Regenerative medicine and anti-aging research have made great strides at the molecular
and cellular levels in dermatology and the medical aesthetic field, targeting potential …

Application and prospect of artificial intelligence in antimicrobial peptides screening

XUE Feng, F Shuo, LI Jing - Journal of China Pharmaceutical …, 2023 - jcpu.cpu.edu.cn
Antimicrobial peptides (AMPs) are a class of small molecule peptides with broad-spectrum
antimicrobial activity. Their unique antimicrobial mechanism can effectively treat infectious …