Two years into the COVID-19 pandemic: lessons learned
SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …
Can COVID-19 vaccines induce premature non-communicable diseases: where are we heading to?
According to the WHO, as of January 2023, more than 850 million cases and over 6.6 million
deaths from COVID-19 have been reported worldwide. Currently, the death rate has been …
deaths from COVID-19 have been reported worldwide. Currently, the death rate has been …
Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids
JM Vanslambrouck, SB Wilson, KS Tan… - Nature …, 2022 - nature.com
While pluripotent stem cell-derived kidney organoids are now being used to model renal
disease, the proximal nephron remains immature with limited evidence for key functional …
disease, the proximal nephron remains immature with limited evidence for key functional …
Human-derived air–liquid interface cultures decipher Alzheimer's disease–SARS-CoV-2 crosstalk in the olfactory mucosa
MA Shahbaz, S Kuivanen, R Lampinen… - Journal of …, 2023 - Springer
Background The neurological effects of the coronavirus disease of 2019 (COVID-19) raise
concerns about potential long-term consequences, such as an increased risk of Alzheimer's …
concerns about potential long-term consequences, such as an increased risk of Alzheimer's …
Single-cell transcriptomics reveals evidence of endothelial dysfunction in the brains of COVID-19 patients with implications for glioblastoma progression
Background: Endothelial dysfunction is implicated in various inflammatory diseases such as
ischemic stroke, heart attack, organ failure, and COVID-19. Recent studies have shown that …
ischemic stroke, heart attack, organ failure, and COVID-19. Recent studies have shown that …
Emerging viral infections and the potential impact on hypertension, cardiovascular disease, and kidney disease
Viruses are ubiquitous in the environment and continue to have a profound impact on
human health and disease. The COVID-19 pandemic has highlighted this with impressive …
human health and disease. The COVID-19 pandemic has highlighted this with impressive …
SARS-CoV-2 ORF3a Protein as a Therapeutic Target against COVID-19 and Long-Term Post-Infection Effects
The COVID-19 pandemic caused by SARS-CoV-2 has posed unparalleled challenges due
to its rapid transmission, ability to mutate, high mortality and morbidity, and enduring health …
to its rapid transmission, ability to mutate, high mortality and morbidity, and enduring health …
Assessing the potential contribution of in silico studies in discovering drug candidates that interact with various SARS-CoV-2 receptors
AGA Mushebenge, SC Ugbaja, NA Mbatha… - International Journal of …, 2023 - mdpi.com
The COVID-19 pandemic has spurred intense research efforts to identify effective treatments
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …
An ultrathin membrane mediates tissue-specific morphogenesis and barrier function in a human kidney chip
Organ-on-chip (OOC) systems are revolutionizing tissue engineering by providing dynamic
models of tissue structure, organ-level function, and disease phenotypes using human cells …
models of tissue structure, organ-level function, and disease phenotypes using human cells …
COVID-19 and the brain: understanding the pathogenesis and consequences of neurological damage
SARS-CoV-2 has been known remarkably since December 2019 as a strain of pathogenic
coronavirus. Starting from the earlier stages of the COVID-19 pandemic until now, we have …
coronavirus. Starting from the earlier stages of the COVID-19 pandemic until now, we have …