The importance of isothiazole and of compounds containing the isothiazole nucleus has
been growing over the last few years. Isothiazolinones are used in cosmetic and as …

Allergic contact dermatitis (ACD) from isothiazolinones has frequently been described in the
literature. Following an epidemic of sensitization to methylchloroisothiazolinone …

The isothiazolinone derivatives, methylchloroisothiazolinone (MCI), methylisothiazolinone
(MI), benzisothiazolinone (BIT), and octylisothiazolinone (OIT), owing to their strong …

Background The use of methylisothiazolinone (MI) in cosmetic products has caused an
unprecedented epidemic of MI contact allergy. Current data concerning exposures at a E …

Background In view of the current epidemic of contact allergy to methylisothiazolinone (MI), it
is important to clarify the extent of use of MI and related isothiazolinones in paints currently …

Background In recent years, the frequency of contact allergy to isothiazolinones has
increased alarmingly in Europe, but only limited data are available on concentrations of …

Driven by regulatory requirements and market demands, the paint industry has replaced
conventional “solvent-based” paints with “water-based” paints containing zero or low …

Abstract The mixture of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT,
chloromethylisothiazolinone) and 2-methyl-4-isothiazolin-3-one (MIT, methylisothiazolinone) …

Due to the Covid-19 pandemic, the worldwide biocides application has been increased,
which will eventually result in enhanced residuals in treated wastewater. At the same time …

Background Airborne allergic contact dermatitis caused by paints containing
isothiazolinones has been recognized as a health hazard. Objectives To collect …