Biological activity of novel organotin compounds with a Schiff base containing an antioxidant fragment

TA Antonenko, YA Gracheva, DB Shpakovsky… - International Journal of …, 2023 - mdpi.com
A series of novel organotin (IV) complexes on the base of 2-(N-3′, 5′-di-tert-butyl-4′-
hydroxyphenyl)-iminomethylphenol (L) of formulae Me2SnBr2 (L) 2 (1), Bu2SnCl2 (L) 2 (2) …

A Cyclometalated Ruthenium (II) Complex Induces Oncosis for Synergistic Activation of Innate and Adaptive Immunity

T Feng, Z Tang, J Shu, X Wu, H Jiang… - Angewandte Chemie …, 2024 - Wiley Online Library
An optimal cancer chemotherapy regimen should effectively address the drug resistance of
tumors while eliciting antitumor‐immune responses. Research has shown that non …

Unveiling the anticancer activity of ruthenium and iron complexes

N Kannan, R Vidya, A Sinha - Inorganic Chemistry Communications, 2024 - Elsevier
Transition metal complexes have a great potential as therapeutic agents in the field of
oncology. Metals are necessary cellular components that are required for various vital …

New organometallic Ru (II) compounds with lonidamine motif as antitumor agents

IA Shutkov, YN Okulova, DM Mazur, NA Melnichuk… - Pharmaceutics, 2023 - mdpi.com
The combination of one molecule of organic and metal-based fragments that exhibit
antitumor activity is a modern approach in the search for new promising drugs. In this work …

Glutathione‐Sensitive Photosensitizer–Drug Conjugates Target the Mitochondria to Overcome Multi‐Drug Resistance in Cancer

W Song, H Yang, Y Wang, S Chen, W Zhong… - Advanced …, 2024 - Wiley Online Library
Multi‐drug resistance (MDR) is a major cause of cancer therapy failure. Photodynamic
therapy (PDT) is a promising modality that can circumvent MDR and synergize with …

Enantiomeric Complexes Based on Ruthenium (III) and 2, 2′-Biimidazole: X-ray Structure and Magnetic Properties

M Orts-Arroyo, J Monfort, N Moliner, J Martínez-Lillo - Molecules, 2023 - mdpi.com
We have prepared and characterized two Ru (III) compounds based on the 2, 2′-
biimidazole (H2biim) ligand, namely, a single complex of formula cis-[RuCl2 (H2biim) 2] Cl …

Organometallic Iridium Complexes with Glucose Based Phosphite Ligands

MR Gonchar, FS Ninin, DM Mazur, KA Lyssenko… - Inorganics, 2023 - mdpi.com
New organometallic iridium compounds with phosphorus modified glucose ligands
containing isopropylidene protection group or bearing uracil, thymine, and 5-fluorouracil (3 …

RuII and RuIII complexes with 2, 6-di-tert-butylphenol ligands: synthesis, electrochemical behaviour, antioxidant properties and antiproliferative activity

AA Antonets, KM Voroshilkina, IA Shutkov… - Mendeleev …, 2024 - Elsevier
New ruthenium (ii) and ruthenium (iii) complexes with 2, 6-di-tert-butylphenol as the
antioxidant moiety were synthesized, and their antioxidant and antiproliferative activities …

Physicochemical characteristics and antiproliferative activity of a water-soluble nanoformulation of the PtIV complex with a lonidamine-based ligand

AA Puchkov, NG Sedush, AA Nazarov… - Russian Chemical …, 2024 - Springer
Water-soluble nanoformulation of a hydrophobic anticancer PtIV complex with a lonidamine-
based ligand has been developed. Biodegradable nanocarriers (13 nm) obtained from poly …

Highly Stable Docetaxel-Loaded Nanoparticles Based on Poly(D,L-lactide)-b-Poly(ethylene glycol) for Cancer Treatment: Preparation, Characterization, and In Vitro …

EV Kuznetsova, NG Sedush, YA Puchkova, SV Aleshin… - Polymers, 2023 - mdpi.com
Stability and narrow size distribution are among the main requirements that apply to drug
formulations based on polymeric nanoparticles. In this study, we obtained a series of …