Epigenetics of male infertility: the role of DNA methylation
JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …
Non-coding RNAs as direct and indirect modulators of epigenetic regulation
VJ Peschansky, C Wahlestedt - Epigenetics, 2014 - Taylor & Francis
Epigenetic regulation of gene expression is an increasingly well-understood concept that
explains much of the contribution of an organism's environment and experience to its …
explains much of the contribution of an organism's environment and experience to its …
[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation
DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …
Epigenetics of discordant monozygotic twins: implications for disease
Monozygotic (MZ) twins share nearly all of their genetic variants and many similar
environments before and after birth. However, they can also show phenotypic discordance …
environments before and after birth. However, they can also show phenotypic discordance …
Exosomal microRNAs in seminal plasma are markers of the origin of azoospermia and can predict the presence of sperm in testicular tissue
Abstract STUDY QUESTION Are exosomal microRNAs (miRNAs) in seminal plasma (SP)
useful as markers of the origin of azoospermia and the presence of sperm in the testis …
useful as markers of the origin of azoospermia and the presence of sperm in the testis …
Semen miRNAs contained in exosomes as non-invasive biomarkers for prostate cancer diagnosis
Although it is specific for prostatic tissue, serum prostate-specific antigen (PSA) screening
has resulted in an over-diagnosis of prostate cancer (PCa) and many unnecessary biopsies …
has resulted in an over-diagnosis of prostate cancer (PCa) and many unnecessary biopsies …
Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility
RG Urdinguio, GF Bayon, M Dmitrijeva… - Human …, 2015 - academic.oup.com
Abstract STUDY QUESTION Are there DNA methylation alterations in sperm that could
explain the reduced biological fertility of male partners from couples with unexplained …
explain the reduced biological fertility of male partners from couples with unexplained …
The biogenesis and functions of piRNAs in human diseases
X Wu, Y Pan, Y Fang, J Zhang, M Xie, F Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
Piwi-interacting RNAs (piRNAs) are a novel type of small noncoding RNAs, which are 26–30
nt in length and bind to Piwi proteins. These short RNAs were originally discovered in …
nt in length and bind to Piwi proteins. These short RNAs were originally discovered in …
Non-coding RNAs, epigenetics, and cancer: tying it all together
HJ Ferreira, M Esteller - Cancer and Metastasis Reviews, 2018 - Springer
While only a small part of the human genome encodes for proteins, biological functions for
the so-called junk genome are increasingly being recognized through high-throughput …
the so-called junk genome are increasingly being recognized through high-throughput …
Epigenetics in fish gametes and early embryo
The spermatozoa and oocyte are very specialized cells which possess the unique ability to
fuse and to produce an embryo. This embryo will develop into a mature organism capable of …
fuse and to produce an embryo. This embryo will develop into a mature organism capable of …