The possible ameliorative role of Moringa oleifera seed oil on sofosbuvir-induced nephrotoxicity in albino rats; histopathological, immunohistochemical and …

HA Mahran, YA Okdah, AA Zaky, SM Arisha - The Journal of Basic and …, 2022 - Springer
Background Hepatitis C is a liver infection caused by the hepatitis C virus (HCV). It can
cause both acute and chronic hepatitis. Sofosbuvir (sofo) is a nucleotide analog inhibitor of …

The possible protective role of selenium on the visual cortex of adult albino rat on exposure to potassium dichromate

SS Anwer, HM Hassanin - Ultrastructural Pathology, 2023 - Taylor & Francis
The visual cortex is very important in mammals for processing of visual information.
Exposure to heavy metals such as potassium dichromate poses serious health threat to …

Effect of sofosbuvir (sovaldi) on the fundic mucosa of adult male albino rats and the possible protective role of fucoidan: Histological, histochemical, and …

DE Elghazouly, RI Yassien - Egyptian Journal of Histology, 2022 - ejh.journals.ekb.eg
Background: Sofosbuvir (SOF) is a hopeful remedy for chronic hepatitis C virus infection.
However, it records some unfavorable influences on gastrointestinal tract. Fucoidan is a …

[HTML][HTML] Effect of sofosbuvir administration and its withdrawal on the submandibular salivary gland of adult male albino rats: A histological and ultra-structural study

AM Abdeen, T Essawy… - Open Access Macedonian …, 2019 - ncbi.nlm.nih.gov
BACKGROUND: Sofosbuvir (SOF) was approved in 2013 as a part of first-line treatment for
hepatitis C virus (HCV); it has activity against all genotypes with extrahepatic adverse effects …

Histological and biochemical studies on effect of Sofosbuvir (Sovaldi) on adult male albino rat kidney

AF Mohamed, AM Abo-Ouf, MAA Arafa - Ultrastructural Pathology, 2021 - Taylor & Francis
Sofosbuvir (sovaldi) is the backbone of many anti‐HCV drugs. We aimed to demonstrate the
effect of sofosbuvir on the adult male albino rat kidney. Sixty adult male albino rats were …

[HTML][HTML] Alveolar process changes associated with administration of nucleos (t) ide analogue (sofosbuvir) in rat model

DBE Farag, DA El-Baz, ZA Salem - Dental and medical problems, 2018 - dmp.umw.edu.pl
Background. Sofosbuvir is a nucleotide compound that has proved to be among the most
potent orally available antiviral treatments. Infrequent but serious adverse events have been …

Histological and Immunohistochemical Study of the Effect of Sofosbuvir and its withdrawal on the Submandibular salivary glands and Tongue of Adult Male Albino …

SM Badr, EM El-Beltagi… - … and Biomedical Journal, 2025 - bbj.journals.ekb.eg
Hepatitis C virus (HCV) infection has been considered a core reason of chronic liver
disorder. Sofosbuvir (SOF) is part of a combined antiviral therapy regimen used to treat …

Extra hepatic effects of sofosbuvir on a serous model of major and minor salivary glands in albino rats

FA Saad, I Aboushady, S Mehanni - Egyptian Journal of Histology, 2020 - journals.ekb.eg
Background: Extra hepatic adverse effects associated with the therapy of chronic HCV
infection with sofosbuvir treatment regimens have recently arisen. Objective: This study …

[PDF][PDF] Ultrastructural and biochemical studies on the potential ef fects of Moringa oleifera seed oil against nephrotoxicity induced by sofosbuvir in albino rats.

HA Mahran, YA Okdah, AA Zaky… - Egyptian Journal of …, 2022 - researchgate.net
The hepatitis C virus (HCV) causes both acute and chronic hepatitis which spread
worldwide and accompanied with severe complications in long period of injury. Sofosbuvir …

The Histopathological Effect of Sofosbuvir as Compared to Sofosbuvir Combined with Ribavirin on Submandibular Salivary Glands of Adult Albino Rats (Histological …

AO Shawkat, ZH Ali, M Bashir - Egyptian Journal of Histology, 2023 - ejh.journals.ekb.eg
Introduction: Sofosbuvir is one of the direct acting antiviral drugs (DAAs) acting on specific
Hepatitis C virus (HCV) target proteins which are important for virus replication and …