[HTML][HTML] Mechanoresponsive metabolism in cancer cell migration and metastasis

MR Zanotelli, J Zhang, CA Reinhart-King - Cell metabolism, 2021 - cell.com
Altered tissue mechanics and metabolism are defining characteristics of cancer that impact
not only proliferation but also migration. While migrating through a mechanically and …

Male breast cancer: a disease distinct from female breast cancer

A Gucalp, TA Traina, JR Eisner, JS Parker… - Breast cancer research …, 2019 - Springer
Purpose Male breast cancer (BC) is rare, representing approximately 1% of cancers that
occur in men and approximately 1% of all BCs worldwide. Because male BC is rare, not …

Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients

C Yau, M Osdoit, M van der Noordaa, S Shad… - The Lancet …, 2022 - thelancet.com
Background Previous studies have independently validated the prognostic relevance of
residual cancer burden (RCB) after neoadjuvant chemotherapy. We used results from …

E-cadherin is required for metastasis in multiple models of breast cancer

V Padmanaban, I Krol, Y Suhail, BM Szczerba, N Aceto… - Nature, 2019 - nature.com
Metastasis is the major driver of death in patients with cancer. Invasion of surrounding
tissues and metastasis have been proposed to initiate following loss of the intercellular …

Head-to-head evaluation of 18F-FES and 18F-FDG PET/CT in metastatic invasive lobular breast cancer

GA Ulaner, K Jhaveri, S Chandarlapaty… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Invasive lobular carcinoma (ILC) demonstrates lower conspicuity on 18F-FDG PET than the
more common invasive ductal carcinoma. Other molecular imaging methods may be needed …

Diagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancer

WA Berg, L Gutierrez, MS NessAiver, WB Carter… - radiology, 2004 - pubs.rsna.org
PURPOSE: To prospectively assess accuracy of mammography, clinical examination,
ultrasonography (US), and magnetic resonance (MR) imaging in preoperative assessment …

The molecular pathology of breast cancer progression

A Bombonati, DC Sgroi - The Journal of pathology, 2011 - Wiley Online Library
The current model of human breast cancer progression proposes a linear multi‐step process
which initiates as flat epithelial atypia (FEA), progresses to atypical ductal hyperplasia …

Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities

Z Huang, Z Zhang, C Zhou, L Liu, C Huang - MedComm, 2022 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …

Fertility preservation in women

J Donnez, MM Dolmans - Nature Reviews Endocrinology, 2013 - nature.com
In women,∼ 10% of cancers occur in those< 45 years old. Chemotherapy, radiotherapy and
bone marrow transplantation can cure> 90% of girls and young women with diseases that …

Invasive lobular carcinoma: an understudied emergent subtype of breast cancer

JA Mouabbi, A Hassan, B Lim, GN Hortobagyi… - Breast cancer research …, 2022 - Springer
Invasive lobular carcinoma (ILC) is the second most common histologic subtype of breast
cancer after invasive ductal carcinoma (IDC), accounting for 10–15% of all breast cancer …