Aflatoxins and fumonisins (FB) are mycotoxins contaminating a large fraction of the world's
food, including maize, cereals, groundnuts and tree nuts. The toxins frequently co-occur in …

The sequence of heterocyclic bases on the interior of the DNA double helix constitutes the
genetic code that drives the operation of all living organisms. With this said, it is not …

Chronic hepatitis B virus (HBV) infection and dietary exposure to aflatoxin B1 (AFB1), two of
the major risk factors in the multifactorial aetiology of hepatocellular carcinoma (HCC), co …

Chronic dietary exposure to aflatoxin B 1 (AFB 1), concomitant with hepatitis B infection is
associated with a significant increased risk for hepatocellular carcinomas (HCCs) in people …

N7-Alkyl-2′-deoxyguanosines are major adducts in DNA that are generated by various
alkylating mutagens and drugs. However, the effect of the N7 alkylation on the hydrogen …

Although most countries regulate the aflatoxin levels in food by legislations, high amounts of
aflatoxin B1 (AFB1)-DNA adducts can still be detected in normal and tumorous tissue …

Toxigenic fungi, including Aspergillus and Fusarium species, contaminate our major cereal
crops with an array of harmful mycotoxins, which threaten the health of humans and farmed …

Cytochrome P450 (P450, CYP) 11A1 is the classical cholesterol side chain cleavage
enzyme (P450 scc) that removes six carbons of the side chain, the first and rate-limiting step …

The genome and its nucleotide precursor pool are under sustained attack by radiation,
reactive oxygen and nitrogen species, chemical carcinogens, hydrolytic reactions, and …

Global distribution of hepatocellular carcinomas (HCCs) is dominated by its incidence in
developing countries, accounting for> 700,000 estimated deaths per year, with dietary …