Immunological prognostic factors in multiple myeloma
Multiple myeloma (MM) is a plasma cell neoplasm characterized by an abnormal
proliferation of clonal, terminally differentiated B lymphocytes. Current approaches for the …
proliferation of clonal, terminally differentiated B lymphocytes. Current approaches for the …
Pathways of angiogenic and inflammatory cytokines in multiple myeloma: role in plasma cell clonal expansion and drug resistance
A Melaccio, A Reale, I Saltarella, V Desantis… - Journal of Clinical …, 2022 - mdpi.com
Multiple myeloma (MM) is the second most common hematological malignancy, and despite
the introduction of innovative therapies, remains an incurable disease. Identifying early and …
the introduction of innovative therapies, remains an incurable disease. Identifying early and …
Molecular and clinical characterization of ANG expression in gliomas and its association with tumor-related immune response
J Wang, A Shan, F Shi, Q Zheng - Frontiers in Medicine, 2023 - frontiersin.org
Background Angiogenin (ANG) has been widely reported as a crucial molecular regulator in
multiple malignancies. However, its role in gliomagenesis remains unclear. This study …
multiple malignancies. However, its role in gliomagenesis remains unclear. This study …
Extracellular vesicles of multiple myeloma cells utilize the proteasome inhibitor mechanism to moderate endothelial angiogenesis
M Zarfati, I Avivi, B Brenner, T Katz, A Aharon - Angiogenesis, 2019 - Springer
Bone marrow microenvironment is known to support angiogenesis, thus contributing to
progression of multiple myeloma (MM). Bortezomib, a proteasome inhibitor (PI) widely used …
progression of multiple myeloma (MM). Bortezomib, a proteasome inhibitor (PI) widely used …
[HTML][HTML] MiR-195 is a key negative regulator of hepatocellular carcinoma metastasis by targeting FGF2 and VEGFA
M Wang, J Zhang, L Tong, X Ma… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common primary tumor of liver and the fifth
most common cancer in the world. Lung is the most frequent site for extra hepatic metastasis …
most common cancer in the world. Lung is the most frequent site for extra hepatic metastasis …
[HTML][HTML] Ginsenoside Rg3 inhibits HIF-1α and VEGF expression in patient with acute leukemia via inhibiting the activation of PI3K/Akt and ERK1/2 pathways
D Zeng, J Wang, P Kong, C Chang, J Li… - International Journal of …, 2014 - ncbi.nlm.nih.gov
Aberrant angiogenesis is essential to the development and progression of leukemia.
Ginsenoside Rg3 has been commonly used in anti-angiogenic therapy of solid tumors. This …
Ginsenoside Rg3 has been commonly used in anti-angiogenic therapy of solid tumors. This …
[HTML][HTML] PDGF upregulates CLEC-2 to induce T regulatory cells
The effect of platelet derived growth factor (PDGF) on immune cells is not elucidated. Here,
we demonstrate PDGF inhibited the maturation of human DCs and induced IL-10 secretion …
we demonstrate PDGF inhibited the maturation of human DCs and induced IL-10 secretion …
[HTML][HTML] Highly expressed integrin-α8 induces epithelial to mesenchymal transition-like features in multiple myeloma with early relapse
Despite recent groundbreaking advances in multiple myeloma (MM) treatment, most MM
patients ultimately experience relapse, and the relapse biology is not entirely understood. To …
patients ultimately experience relapse, and the relapse biology is not entirely understood. To …
[HTML][HTML] Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression
Despite the advent of many therapeutic agents, such as bortezomib and lenalidomide that
have significantly improved the overall survival, multiple myeloma remains an incurable …
have significantly improved the overall survival, multiple myeloma remains an incurable …
Extracellular vesicles as potential biomarkers of acute graft-vs-host disease
Acute graft-vs-host disease (GVHD) is a serious complication after allografting. We carried
out an exploratory study to investigate a potential correlation of surface antigens on …
out an exploratory study to investigate a potential correlation of surface antigens on …