Successes and challenges of HIV prevention in men who have sex with men
Men who have sex with men (MSM) have been substantially affected by HIV epidemics
worldwide. Epidemics in MSM are re-emerging in many high-income countries and gaining …
worldwide. Epidemics in MSM are re-emerging in many high-income countries and gaining …
Antiretroviral therapy for prevention of HIV transmission in HIV‐discordant couples
Background Antiretroviral drugs have been shown to reduce risk of mother‐to‐child
transmission of human immunodeficiency virus (HIV) and are also widely used for post …
transmission of human immunodeficiency virus (HIV) and are also widely used for post …
[HTML][HTML] Antiretroviral therapy for the prevention of HIV-1 transmission
Background An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052
trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked …
trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked …
[HTML][HTML] Prevention of HIV-1 infection with early antiretroviral therapy
Background Antiretroviral therapy that reduces viral replication could limit the transmission
of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods In nine …
of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods In nine …
Increased risk of HIV acquisition among women throughout pregnancy and during the postpartum period: a prospective per-coital-act analysis among women with HIV …
KA Thomson, J Hughes, JM Baeten… - The Journal of …, 2018 - academic.oup.com
Background Understanding the absolute and relative risk of human immunodeficiency virus
type 1 (HIV) acquisition during pregnancy and the postpartum period can inform HIV …
type 1 (HIV) acquisition during pregnancy and the postpartum period can inform HIV …
Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here?
Antiretroviral drugs that inhibit viral replication were expected to reduce transmission of HIV
by lowering the concentration of HIV in the genital tract. In 11 of 13 observational studies …
by lowering the concentration of HIV in the genital tract. In 11 of 13 observational studies …
[HTML][HTML] TreeCluster: Clustering biological sequences using phylogenetic trees
Clustering homologous sequences based on their similarity is a problem that appears in
many bioinformatics applications. The fact that sequences cluster is ultimately the result of …
many bioinformatics applications. The fact that sequences cluster is ultimately the result of …
Defining HIV-1 transmission clusters based on sequence data
AS Hassan, OG Pybus, EJ Sanders, J Albert… - Aids, 2017 - journals.lww.com
Understanding HIV-1 transmission dynamics is relevant to both screening and intervention
strategies of HIV-1 infection. Commonly, HIV-1 transmission chains are determined based …
strategies of HIV-1 infection. Commonly, HIV-1 transmission chains are determined based …
[HTML][HTML] Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing data
Many viruses, including the clinically relevant RNA viruses HIV (human immunodeficiency
virus) and HCV (hepatitis C virus), exist in large populations and display high genetic …
virus) and HCV (hepatitis C virus), exist in large populations and display high genetic …
[HTML][HTML] Systematic review of HIV transmission between heterosexual serodiscordant couples where the HIV-positive partner is fully suppressed on antiretroviral …
MR Loutfy, W Wu, M Letchumanan, L Bondy… - PloS one, 2013 - journals.plos.org
Background The risk of sexual HIV transmission in serodiscordant couples when the HIV-
positive partner has full virologic suppression on combination antiretroviral therapy (cART) is …
positive partner has full virologic suppression on combination antiretroviral therapy (cART) is …