Severe obesity is a rapidly growing global health threat. Although often attributed to
unhealthy lifestyle choices or environmental factors, obesity is known to be heritable and …

Background Following wider acceptance of 'the thrifty phenotype'hypothesis and the
convincing evidence that early‐life exposures can influence adult health even decades after …

There is an enormous interest in identifying the causes of psychiatric disorders but there are
considerable challenges in identifying which risks are genuinely causal. Traditionally risk …

Importance Schizophrenia is associated with major cognitive deficits and has been
conceptualized as both a neurodevelopmental and a neurodegenerative disorder. However …

Depression is a common mental illness and research has focused on late childhood and
adolescence in an attempt to prevent or reduce later psychopathology and/or social …

Background Prenatal air pollution exposure may increase risk for childhood obesity.
However, few studies have evaluated in utero growth measures and infant weight …

Background Dietary and illness factors affect risk of growth faltering; the role of
enteropathogens is less clear. As part of the Etiology, Risk Factors and Interactions of …

Background: Statistical models that use an individual's DNA methylation levels to estimate
their age (known as epigenetic clocks) have recently been developed, with 96% correlation …

Background In many parts of the world policy and research interventions to modify sedentary
behavior of children and adolescents are now being developed. However, the evidence to …

Importance Evidence that breastfeeding reduces child obesity risk and lowers blood
pressure (BP) is based on potentially confounded observational studies. Objective To …