The pathogenesis of endometriosis: molecular and cell biology insights

AS Laganà, S Garzon, M Götte, P Viganò… - International journal of …, 2019 - mdpi.com
The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

[HTML][HTML] New developments in the medical treatment of endometriosis

MA Bedaiwy, S Alfaraj, P Yong, R Casper - Fertility and sterility, 2017 - Elsevier
Endometriosis affects 1 in 10 women of reproductive-age. The current treatments are
surgical and hormonal but have limitations, including the risk of recurrence, side effects …

Gut microbiota–derived short-chain fatty acids protect against the progression of endometriosis

SB Chadchan, P Popli, CR Ambati… - Life science …, 2021 - life-science-alliance.org
Worldwide,∼ 196 million are afflicted with endometriosis, a painful disease in which
endometrial tissue implants and proliferates on abdominal peritoneal surfaces. Theories on …

Epigenetics of endometriosis

SW Guo - Molecular human reproduction, 2009 - academic.oup.com
Endometriosis is a common gynecologic disorder with an enigmatic etiopathogenesis.
Although it has been proposed that endometriosis is a hormonal disease, an autoimmune …

Epigenetic dysregulation in endometriosis: implications for pathophysiology and therapeutics

RM Marquardt, DN Tran, BA Lessey… - Endocrine …, 2023 - academic.oup.com
Endometriosis is a prevalent gynecological condition associated with pelvic pain and
infertility. Despite more than a century of research, the etiology of endometriosis still eludes …

[HTML][HTML] Pharmacologic therapies in endometriosis: a systematic review

SR Soares, A Martínez-Varea, JJ Hidalgo-Mora… - Fertility and sterility, 2012 - Elsevier
To assess the literature on preclinical and clinical efficacy and safety data of pharmacologic
groups proposed in the treatment of endometriosis, we performed a systematic review of …

Angiogenesis and endometriosis

ALL Rocha, FM Reis, RN Taylor - Obstetrics and gynecology …, 2013 - Wiley Online Library
A comprehensive review was performed to survey the role of angiogenesis in the
pathogenesis of endometriosis. This is a multifactorial disease in which the development …

Anti-angiogenic treatment strategies for the therapy of endometriosis

MW Laschke, MD Menger - Human reproduction update, 2012 - academic.oup.com
BACKGROUND Angiogenesis, ie the development of new blood vessels from pre-existing
ones, represents an integral part in the pathogenesis of endometriosis. During the last …

Transforming growth factor-β induced Warburg-like metabolic reprogramming may underpin the development of peritoneal endometriosis

VJ Young, JK Brown, J Maybin… - The Journal of …, 2014 - academic.oup.com
Context: TGF-β is believed to play a major role in the etiology of peritoneal endometriosis. In
tumors, TGF-β induces the metabolic conversion of glucose to lactate via glycolysis, a …

Histone deacetylases inhibitors (HDACis) as novel therapeutic application in various clinical diseases

X Qiu, X Xiao, N Li, Y Li - Progress in Neuro-Psychopharmacology and …, 2017 - Elsevier
Accumulating evidence suggests that histone hypoacetylation which is partly mediated by
histone deacetylase (HDAC), plays a causative role in the etiology of various clinical …