cis-Regulatory Elements in Plant Development, Adaptation, and Evolution

AP Marand, AL Eveland, K Kaufmann… - Annual review of …, 2023 - annualreviews.org
cis-Regulatory elements encode the genomic blueprints that ensure the proper
spatiotemporal patterning of gene expression necessary for appropriate development and …

Mind the gap: epigenetic regulation of chromatin accessibility in plants

J Candela-Ferre, B Diego-Martin… - Plant …, 2024 - academic.oup.com
Chromatin plays a crucial role in genome compaction and is fundamental for regulating
multiple nuclear processes. Nucleosomes, the basic building blocks of chromatin, are …

Elucidating the biology of transcription factor–DNA interaction for accurate identification of cis-regulatory elements

M Hajheidari, SC Huang - Current opinion in plant biology, 2022 - Elsevier
Transcription factors (TFs) play a critical role in determining cell fate decisions by integrating
developmental and environmental signals through binding to specific cis-regulatory …

Predicting the unpredictable: the regulatory nature and promiscuity of herbicide cross resistance

LK Bobadilla, PJ Tranel - Pest Management Science, 2024 - Wiley Online Library
The emergence of herbicide‐resistant weeds is a significant threat to modern agriculture.
Cross resistance, a phenomenon where resistance to one herbicide confers resistance to …

Genomic survey of TCP transcription factors in plants: Phylogenomics, evolution and their biology

H Zhou, D Hwarari, H Ma, H Xu, L Yang, Y Luo - Frontiers in genetics, 2022 - frontiersin.org
The TEOSINTE BRANCHED1 (TBI1), CYCLOIDEA (CYC), and PROLIFERATING CELL
NUCLEAR ANTIGEN FACTORS (PCF1 and PCF2) proteins truncated as TCP transcription …

MINI‐AC: inference of plant gene regulatory networks using bulk or single‐cell accessible chromatin profiles

N Manosalva Pérez, C Ferrari, J Engelhorn… - The Plant …, 2024 - Wiley Online Library
Gene regulatory networks (GRNs) represent the interactions between transcription factors
(TF) and their target genes. Plant GRNs control transcriptional programs involved in growth …

Genetic dissection of cis-regulatory control of ZmWUSCHEL1 expression by type B RESPONSE REGULATORS

Z Chen, L Cortes, A Gallavotti - Plant physiology, 2024 - academic.oup.com
Mutations in cis-regulatory regions play an important role in the domestication and
improvement of crops by altering gene expression. However, assessing the in vivo impact of …

Mapping responsive genomic elements to heat stress in a maize diversity panel

Z Liang, ZA Myers, D Petrella, J Engelhorn, T Hartwig… - Genome biology, 2022 - Springer
Background Many plant species exhibit genetic variation for coping with environmental
stress. However, there are still limited approaches to effectively uncover the genomic region …

Modeling 0.6 million genes for the rational design of functional cis-regulatory variants and de novo design of cis-regulatory sequences

T Li, H Xu, S Teng, M Suo, R Bahitwa… - Proceedings of the …, 2024 - National Acad Sciences
Rational design of plant cis-regulatory DNA sequences without expert intervention or prior
domain knowledge is still a daunting task. Here, we developed PhytoExpr, a deep learning …

Deep learning the cis-regulatory code for gene expression in selected model plants

FF Peleke, SM Zumkeller, M Gültas, A Schmitt… - Nature …, 2024 - nature.com
Elucidating the relationship between non-coding regulatory element sequences and gene
expression is crucial for understanding gene regulation and genetic variation. We explored …